Role of Azithromycin on Dengue Associated Enteric Fever: A Cross Sectional Study

Introduction

DENGUE is one of the most frequent communicable diseases in rainy season. Along with enteric fever this year patients frequently affected by this disease which was worsen in some cases. Though DENGUE associated enteric fever is not so much common, it's management by Tab AZITHROMYCIN bring an effective outcome with reduced hospital admission.

Methods

68(age interval 24-59(+-2years) patients with history of fever who came in emergency & OPD (outdoor patient department)participated in this cross sectional study. 39 of them diagnosed DENGUE associated enteric fever based on relevant investigations like blood culture sensitivity, DENGUE NS1 and DENGUE IgM & IgG. 2

Results

6 patients comparatively feel better who refused hospital admission and seek for oral medications although having high WBC (White blood cells) counts in their CBC reports.3 of them (11.53%) were excluded for irrational drugs abuse .Rest of 23 patients (88.46%) had history of maintaining rational antibiotics . 15 patients came for follow up within 3 weeks specially for further CBC reviewing although they are mostly asymptomatic comparing with previous state. CBC reports of 12 patients indicate decrease WBC count(ranging 7000-9500 / mm^3) whose previous WBC range 11,000- 14000/mm^3 of blood. 3 patients have found constant leukocytosis though it is overlooked(p<0.05).

Conclusion

DENGUE associated enteric fever can be managed under home observation by rational AZITHROMYCIN uses which can bring a new era in clinical field of Bangladesh. But it should be monitored with rational antibiotic use.