大剂量支气管扩张剂治疗慢性支气管炎的雾化雾化器与雾化雾化器的比较

Martin B. Allen, Jenny Pugh, Robert S.E. Wilson
{"title":"大剂量支气管扩张剂治疗慢性支气管炎的雾化雾化器与雾化雾化器的比较","authors":"Martin B. Allen,&nbsp;Jenny Pugh,&nbsp;Robert S.E. Wilson","doi":"10.1016/0007-0971(88)90090-3","DOIUrl":null,"url":null,"abstract":"<div><p>We have compared the clinical efficacy of high dose terbutaline sulphate (10 mg four times daily) delivered by either a Nebuhaler or jet nebulizer in 13 patients with chronic bronchitis in a 2-week, open, crossover study.</p><p>Both treatment regimens improved run-in symptom scores but no significant changes were recorded in peak flow and spirometry. Side-effects were more common with the Nebuhaler and more patients preferred the nebulizer. However, the Nebuhaler is an alternative therapeutic option for delivery of high doses of bronchodilators in patients with chronic bronchitis.</p></div>","PeriodicalId":75618,"journal":{"name":"British journal of diseases of the chest","volume":"82 ","pages":"Pages 368-373"},"PeriodicalIF":0.0000,"publicationDate":"1988-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0007-0971(88)90090-3","citationCount":"9","resultStr":"{\"title\":\"Nebuhaler or nebulizer for high dose bronchodilator therapy in chronic bronchitis: a comparison\",\"authors\":\"Martin B. Allen,&nbsp;Jenny Pugh,&nbsp;Robert S.E. Wilson\",\"doi\":\"10.1016/0007-0971(88)90090-3\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>We have compared the clinical efficacy of high dose terbutaline sulphate (10 mg four times daily) delivered by either a Nebuhaler or jet nebulizer in 13 patients with chronic bronchitis in a 2-week, open, crossover study.</p><p>Both treatment regimens improved run-in symptom scores but no significant changes were recorded in peak flow and spirometry. Side-effects were more common with the Nebuhaler and more patients preferred the nebulizer. However, the Nebuhaler is an alternative therapeutic option for delivery of high doses of bronchodilators in patients with chronic bronchitis.</p></div>\",\"PeriodicalId\":75618,\"journal\":{\"name\":\"British journal of diseases of the chest\",\"volume\":\"82 \",\"pages\":\"Pages 368-373\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1988-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/0007-0971(88)90090-3\",\"citationCount\":\"9\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"British journal of diseases of the chest\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/0007097188900903\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"British journal of diseases of the chest","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/0007097188900903","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 9

摘要

在一项为期2周的开放交叉研究中,我们比较了高剂量特布他林硫酸盐(10mg,每日4次)由Nebuhaler或喷射雾化器给药13例慢性支气管炎患者的临床疗效。两种治疗方案均改善了磨合症状评分,但在峰值流量和肺活量方面没有显著变化。副作用更常见的Nebuhaler和更多的患者喜欢雾化器。然而,Nebuhaler是慢性支气管炎患者给予高剂量支气管扩张剂的另一种治疗选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nebuhaler or nebulizer for high dose bronchodilator therapy in chronic bronchitis: a comparison

We have compared the clinical efficacy of high dose terbutaline sulphate (10 mg four times daily) delivered by either a Nebuhaler or jet nebulizer in 13 patients with chronic bronchitis in a 2-week, open, crossover study.

Both treatment regimens improved run-in symptom scores but no significant changes were recorded in peak flow and spirometry. Side-effects were more common with the Nebuhaler and more patients preferred the nebulizer. However, the Nebuhaler is an alternative therapeutic option for delivery of high doses of bronchodilators in patients with chronic bronchitis.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信