2002 年至 2015 年美国输卵管绝育后的怀孕情况。

NEJM evidence Pub Date : 2024-09-01 Epub Date: 2024-08-27 DOI:10.1056/EVIDoa2400023
Eleanor Bimla Schwarz, Amy Yunyu Chiang, Carrie A Lewis, Aileen M Gariepy, Matthew F Reeves
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引用次数: 0

摘要

背景:输卵管绝育是美国最常用的避孕方法。由于避孕效果会影响避孕方法的选择,我们研究了美国输卵管绝育后的典型使用失败率:我们利用 2002 年、2006 年至 2010 年、2011 年至 2013 年以及 2013 年至 2015 年四次全国家庭成长调查(NSFG)的数据估算了输卵管绝育后的怀孕率。在生存分析中使用了调查加权来研究输卵管绝育后首次怀孕的时间。这些参与者的数据在输卵管逆转术、不孕症治疗、子宫切除术或双侧输卵管切除术后被删除。使用 Kaplan-Meier 曲线和多变量 Cox 比例危险模型对报告的输卵管绝育手术后怀孕率进行检验,以研究输卵管绝育手术时的年龄、种族/民族、教育程度、医疗补助资金以及产后手术与间隔手术的影响:据报告,2.9% 至 5.2%的参与者在输卵管绝育手术后怀孕。在最近一次调查(2013 年至 2015 年)中,输卵管绝育手术后 12 个月内怀孕的参与者估计占 2.9%;输卵管绝育手术后 120 个月内怀孕的参与者估计占 8.4%。在所有检查的时间点上,产后输卵管绝育手术后怀孕的几率都低于间隔期手术后怀孕的几率;但在多变量模型中,这种差异并不明显。在多变量模型中,怀孕几率随输卵管绝育时年龄的增长而降低。种族/民族、教育程度和医疗补助资金与输卵管绝育后怀孕的关系并不一致:这些数据表明,输卵管绝育后的怀孕率可能并不高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Pregnancy after Tubal Sterilization in the United States, 2002 to 2015.

Background: Tubal sterilization is the most commonly used method of contraception in the United States. Because contraceptive effectiveness influences contraceptive selection, we examined typical use failure rates after tubal sterilization in the United States.

Methods: We estimated rates of pregnancy after tubal sterilization using data from four waves of the National Survey of Family Growth (NSFG), representative samples of U.S. women aged 15 to 44 years, collected in 2002, 2006 to 2010, 2011 to 2013, and 2013 to 2015. Survey weighting was used in survival analysis to examine time to first pregnancy after tubal sterilization. Data from these participants were censored after a tubal reversal procedure, infertility treatment, hysterectomy, or bilateral oophorectomy. Reported pregnancy rates after tubal sterilization procedures were examined by using Kaplan-Meier curves and then multivariable Cox proportional-hazards models to examine the effects of age at tubal sterilization, race/ethnicity, education, Medicaid funding, and postpartum versus interval procedures.

Results: Pregnancy after tubal sterilization was reported by 2.9 to 5.2% of participants across NSFG waves. In the most recent survey wave (2013 to 2015), the estimated percentage of participants with pregnancies within the first 12 months after a tubal sterilization procedure was 2.9%; at 120 months after tubal sterilization, the estimated percentage with a pregnancy was 8.4%. At all the time points examined, pregnancy after tubal sterilization was less common after postpartum procedures than after interval procedures; however, this difference was not evident in multivariable models. In multivariable models, chance of pregnancy decreased with age at time of tubal sterilization. Race/ethnicity, education, and Medicaid funding were not consistently associated with pregnancy after tubal sterilization.

Conclusions: These data suggest that there may be nontrivial rates of pregnancy after tubal sterilization.

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