Guillermo Sánchez-Fonseca , María del Carmen Soler-Ruiz , María Dolores Fonseca-Montosa , Francisco Rafael Sánchez-Sánchez , Marta Sánchez-Aguilar , Roberto Domingo Tabernero-Rico , Miguel Ángel Corral-de Calle
{"title":"骨质疏松症:病例报告","authors":"Guillermo Sánchez-Fonseca , María del Carmen Soler-Ruiz , María Dolores Fonseca-Montosa , Francisco Rafael Sánchez-Sánchez , Marta Sánchez-Aguilar , Roberto Domingo Tabernero-Rico , Miguel Ángel Corral-de Calle","doi":"10.1016/j.rmclc.2024.04.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Clinical case</h3><p>A 42-year-old woman, a smoker since her twenties, without any personal, family or traumatic history of interest. Currently, she consults with a cold like symptoms with fever that has lasted for several days. She had right chest and abdominal pain without dyspnea, with pleuritic characteristics. refractory to ibuprofen.</p></div><div><h3>Results</h3><p>A chest x-ray was performed showing several pulmonary micronodules, which, added to her smoking history and refractory thoraco-abdominal pain, prompted a thoraco-abdomino-pelvic computerized tomography (CT). On CT, the pulmonary micronodular images do not appear to have a malignant behavior, but since they are associated with multiple enostotic infiltrative osteosclerotic lesions in the axial skeleton (incidentally seen on thoraco-abdomino-pelvic CT with bone window), their better characterization with a metabolic study is recommended, given the reasonable suspicion of bone metastases secondary to lung cancer. In the metabolic/functional extension study, a global hypouptake was obtained, reasonably ruling out the possibility of bone metastases, and directing diagnostic suspicions towards other benign possibilities such osteopoikilosis.</p></div><div><h3>Conclusions</h3><p>Osteopoikilosis is a casual and rare finding that should be included in the differential diagnosis of multiple osteosclerotic images, and not be confused with malignant entities.</p></div>","PeriodicalId":31544,"journal":{"name":"Revista Medica Clinica Las Condes","volume":"35 3","pages":"Pages 336-340"},"PeriodicalIF":0.2000,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S071686402400049X/pdfft?md5=13d69c7613fe8579c669fd81f8c366a1&pid=1-s2.0-S071686402400049X-main.pdf","citationCount":"0","resultStr":"{\"title\":\"Osteopoiquilosis: a propósito de un caso\",\"authors\":\"Guillermo Sánchez-Fonseca , María del Carmen Soler-Ruiz , María Dolores Fonseca-Montosa , Francisco Rafael Sánchez-Sánchez , Marta Sánchez-Aguilar , Roberto Domingo Tabernero-Rico , Miguel Ángel Corral-de Calle\",\"doi\":\"10.1016/j.rmclc.2024.04.004\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Clinical case</h3><p>A 42-year-old woman, a smoker since her twenties, without any personal, family or traumatic history of interest. Currently, she consults with a cold like symptoms with fever that has lasted for several days. She had right chest and abdominal pain without dyspnea, with pleuritic characteristics. refractory to ibuprofen.</p></div><div><h3>Results</h3><p>A chest x-ray was performed showing several pulmonary micronodules, which, added to her smoking history and refractory thoraco-abdominal pain, prompted a thoraco-abdomino-pelvic computerized tomography (CT). On CT, the pulmonary micronodular images do not appear to have a malignant behavior, but since they are associated with multiple enostotic infiltrative osteosclerotic lesions in the axial skeleton (incidentally seen on thoraco-abdomino-pelvic CT with bone window), their better characterization with a metabolic study is recommended, given the reasonable suspicion of bone metastases secondary to lung cancer. In the metabolic/functional extension study, a global hypouptake was obtained, reasonably ruling out the possibility of bone metastases, and directing diagnostic suspicions towards other benign possibilities such osteopoikilosis.</p></div><div><h3>Conclusions</h3><p>Osteopoikilosis is a casual and rare finding that should be included in the differential diagnosis of multiple osteosclerotic images, and not be confused with malignant entities.</p></div>\",\"PeriodicalId\":31544,\"journal\":{\"name\":\"Revista Medica Clinica Las Condes\",\"volume\":\"35 3\",\"pages\":\"Pages 336-340\"},\"PeriodicalIF\":0.2000,\"publicationDate\":\"2024-05-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S071686402400049X/pdfft?md5=13d69c7613fe8579c669fd81f8c366a1&pid=1-s2.0-S071686402400049X-main.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica Clinica Las Condes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S071686402400049X\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica Clinica Las Condes","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S071686402400049X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
A 42-year-old woman, a smoker since her twenties, without any personal, family or traumatic history of interest. Currently, she consults with a cold like symptoms with fever that has lasted for several days. She had right chest and abdominal pain without dyspnea, with pleuritic characteristics. refractory to ibuprofen.
Results
A chest x-ray was performed showing several pulmonary micronodules, which, added to her smoking history and refractory thoraco-abdominal pain, prompted a thoraco-abdomino-pelvic computerized tomography (CT). On CT, the pulmonary micronodular images do not appear to have a malignant behavior, but since they are associated with multiple enostotic infiltrative osteosclerotic lesions in the axial skeleton (incidentally seen on thoraco-abdomino-pelvic CT with bone window), their better characterization with a metabolic study is recommended, given the reasonable suspicion of bone metastases secondary to lung cancer. In the metabolic/functional extension study, a global hypouptake was obtained, reasonably ruling out the possibility of bone metastases, and directing diagnostic suspicions towards other benign possibilities such osteopoikilosis.
Conclusions
Osteopoikilosis is a casual and rare finding that should be included in the differential diagnosis of multiple osteosclerotic images, and not be confused with malignant entities.