人重组 FSH 在黄体酮注射发情同步计划中提高母羊繁殖性能的效果

IF 1.6 3区 农林科学 Q2 AGRICULTURE, DAIRY & ANIMAL SCIENCE
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引用次数: 0

摘要

探索安全、廉价、高效的促性腺激素来提高母羊的繁殖性能是全世界的需求。本研究的目的是探讨在母羊繁殖季节,在注射短效黄体酮的发情同步程序结束后使用人重组 FSH(hrFSH)的可能性。在繁殖季节,采用 2(hrFSH 或无 hrFSH)乘 2(交配或腹腔镜人工授精;LapAI)的因子设计,将夏尔母羊(n=184)随机分配到 4 个组。实验第 0 天,母羊接受黄体酮(37.5 毫克;sc)和 GnRH 类似物(7.5 微克醋酸阿拉瑞林;im)。第 3 天和第 6 天,母羊分别接受 25 毫克和 12.5 毫克黄体酮(sc)。第 6 天,所有母羊均服用前列腺素 F2α 类似物(250 µg Cloprostenol;im)。第 7 天,母羊被分成两个相同的组,分别接受 hrFSH(75 IU Follitropin alfa;sc)或不接受任何进一步治疗。每组发情的母羊被分配交配 5 天,或在发情检测后 4-10 或 20-24 h 进行 LapAI。数据采用 GLM 和 Genmod 程序进行分析。hrFSH 组(89.4%)24 小时内发情同步的紧密度高于无 hrFSH 组(63.9%)(P<0.0001)。hrFSH 组的多产率和受胎率(1.81 和 0.96)分别高于无 hrFSH 组(1.26 和 0.68)(P<0.05)。与 LapAI(45.5 % 和 0.68;P<0.05)相比,交配母羊的产羔率和受胎率分别更高(61.9 % 和 0.96;P<0.05)。发情后 4 至 10 小时内授精的母羊与 20 至 24 小时内授精的母羊(0.64,P<0.05)相比,雄性后代的性别比更高(1.89)。总之,在基于黄体酮注射的母羊发情同步化方案中,hrFSH可被视为一种有效的促性腺激素,用于提高发情同步化的紧密性、多产性和繁殖力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effectiveness of human recombinant FSH for enhancing reproductive performance of ewes in progesterone injection-based estrus synchronization program

Exploring the safe, cheap, and efficient gonadotropin to enhance reproductive performance of ewe is of worldwide demand. The purpose of this study was to examine the possibility of using human recombinant FSH (hrFSH) at the end of a short progesterone injection-based estrus synchronization program during the breeding season in ewe. Shal ewes (n=184) were assigned randomly into 4 groups using 2 (hrFSH or No-hrFSH) by 2 (Mating or Laparoscopic artificial insemination; LapAI) factorial design during the breeding season. On Day 0 of the experiment, ewes received progesterone (37.5 mg; sc) and GnRH analogue (7.5 µg Alarelin acetate; im). On Days 3 and 6, ewes received 25 and 12.5 mg progesterone (sc), respectively. All ewes received prostaglandin F2α analogue (250 µg Cloprostenol; im) on Day 6. On Day 7, ewes were divided into two equal groups and received hrFSH (75 IU Follitropin alfa; sc) or didn’t receive any further treatment. Ewes displaying estrus in each group were assigned for mating for 5 days or LapAI at either 4–10 or 20–24 h after estrous detection. Data were analyzed using GLM and Genmod procedures. The tightness of estrus synchrony within 24 h was greater in hrFSH (89.4 %) than No-hrFSH (63.9 %) group (P<0.0001). The respective prolificacy and fecundity were greater in hrFSH (1.81 and 0.96) than No-hrFSH (1.26 and 0.68) group (P<0.05). The respective lambing rate and fecundity rate were greater for ewes mated (61.9 % and 0.96) compared to LapAI (45.5 % and 0.68; P<0.05). Ewes inseminated between 4 and 10 hours after estrous expression had greater sex ratio toward male offspring (1.89) compared to those inseminated between 20 and 24 hours (0.64, P<0.05). In conclusion, hrFSH could be considered as an effective gonadotropin for enhancing the tightness of estrus synchrony, prolificacy and fecundity in the progesterone injection-based estrus synchronization program in ewe.

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来源期刊
Small Ruminant Research
Small Ruminant Research 农林科学-奶制品与动物科学
CiteScore
3.10
自引率
11.10%
发文量
210
审稿时长
12.5 weeks
期刊介绍: Small Ruminant Research publishes original, basic and applied research articles, technical notes, and review articles on research relating to goats, sheep, deer, the New World camelids llama, alpaca, vicuna and guanaco, and the Old World camels. Topics covered include nutrition, physiology, anatomy, genetics, microbiology, ethology, product technology, socio-economics, management, sustainability and environment, veterinary medicine and husbandry engineering.
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