苯胺的对位选择性 C-H 功能化：综述

IF 2.1 3区化学 Q3 CHEMISTRY, INORGANIC & NUCLEAR

Journal of Organometallic Chemistry Pub Date : 2024-08-16 DOI:10.1016/j.jorganchem.2024.123313

Fatemeh Doraghi , Yasin Mohammadkhani Kalooei , Negar Mehdi Zadeh Darban , Bagher Larijani , Mohammad Mahdavi

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引用次数: 0

摘要

控制苯胺 C-H 功能化的位点选择性是合成化学中的一大挑战。考虑到苯胺衍生物在制药、农用化学品和先进材料中的大量应用，这些支架的副选择官能化受到了广泛关注。本综述重点介绍了有关伯、仲和叔苯胺副选择官能化的各种合成方法，包括亲电芳香反应、亲核芳香反应、氧化加成、自由基加成和类羰基加成。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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para-Selective C-H Functionalization of Anilines: A Review

Controlling the site-selectivity in the C-H functionalization of anilines is one of the great challenges in synthetic chemistry. Considering the numerous applications of aniline derivatives in pharmaceuticals, agrochemicals and advanced materials, the para-selective functionalization of these scaffolds has received much attention. Various synthetic methods on the para-selective functionalization of primary, secondary and tertiary anilines, including electrophilic aromatic reactions, nucleophilic aromatic reactions, oxidative addition, radical addition, and carbenoid addition are highlighted in this review.

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来源期刊

Journal of Organometallic Chemistry 化学-无机化学与核化学

CiteScore

4.40

自引率

8.70%

发文量

221

审稿时长

36 days

期刊介绍： The Journal of Organometallic Chemistry targets original papers dealing with theoretical aspects, structural chemistry, synthesis, physical and chemical properties (including reaction mechanisms), and practical applications of organometallic compounds. Organometallic compounds are defined as compounds that contain metal - carbon bonds. The term metal includes all alkali and alkaline earth metals, all transition metals and the lanthanides and actinides in the Periodic Table. Metalloids including the elements in Group 13 and the heavier members of the Groups 14 - 16 are also included. The term chemistry includes syntheses, characterizations and reaction chemistry of all such compounds. Research reports based on use of organometallic complexes in bioorganometallic chemistry, medicine, material sciences, homogeneous catalysis and energy conversion are also welcome. The scope of the journal has been enlarged to encompass important research on organometallic complexes in bioorganometallic chemistry and material sciences, and of heavier main group elements in organometallic chemistry. The journal also publishes review articles, short communications and notes.