{"title":"环境对特应性湿疹的影响。","authors":"Wismmy Lee, Fihr Chaudhary, Devendra K Agrawal","doi":"10.26502/jesph.96120209","DOIUrl":null,"url":null,"abstract":"<p><p>The health outcomes of an individual are shaped by a combination of genetic predisposition and environmental influences. While some diseases stem solely from environmental factors, others like atopic eczema, also known as neurodermatitis or atopic dermatitis, are multifaceted, with environmental variables playing a significant role in its initiation and severity. Atopic eczema is a prevalent chronic condition observed globally, particularly in Western industrialized nations where its prevalence is estimated to range from 2.5% to 3.5% in adults and 10% to 15% among children. The increasing incidence of atopic eczema in industrialized countries over recent decades suggests that this trend may be due to environmental changes rather than genetic predispositions. Therefore, by thoroughly examining environmental factors and their role in atopic dermatitis, one may be able to gain a better understanding of its disease pattern and develop possible preventative measures. This article provides a comprehensive analysis of how the surrounding environment contributes to the pathogenesis of atopic eczema.</p>","PeriodicalId":73740,"journal":{"name":"Journal of environmental science and public health","volume":"8 2","pages":"101-115"},"PeriodicalIF":0.0000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11328973/pdf/","citationCount":"0","resultStr":"{\"title\":\"Environmental Influences on Atopic Eczema.\",\"authors\":\"Wismmy Lee, Fihr Chaudhary, Devendra K Agrawal\",\"doi\":\"10.26502/jesph.96120209\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The health outcomes of an individual are shaped by a combination of genetic predisposition and environmental influences. While some diseases stem solely from environmental factors, others like atopic eczema, also known as neurodermatitis or atopic dermatitis, are multifaceted, with environmental variables playing a significant role in its initiation and severity. Atopic eczema is a prevalent chronic condition observed globally, particularly in Western industrialized nations where its prevalence is estimated to range from 2.5% to 3.5% in adults and 10% to 15% among children. The increasing incidence of atopic eczema in industrialized countries over recent decades suggests that this trend may be due to environmental changes rather than genetic predispositions. Therefore, by thoroughly examining environmental factors and their role in atopic dermatitis, one may be able to gain a better understanding of its disease pattern and develop possible preventative measures. This article provides a comprehensive analysis of how the surrounding environment contributes to the pathogenesis of atopic eczema.</p>\",\"PeriodicalId\":73740,\"journal\":{\"name\":\"Journal of environmental science and public health\",\"volume\":\"8 2\",\"pages\":\"101-115\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11328973/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of environmental science and public health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.26502/jesph.96120209\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/6/13 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of environmental science and public health","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.26502/jesph.96120209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/6/13 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
The health outcomes of an individual are shaped by a combination of genetic predisposition and environmental influences. While some diseases stem solely from environmental factors, others like atopic eczema, also known as neurodermatitis or atopic dermatitis, are multifaceted, with environmental variables playing a significant role in its initiation and severity. Atopic eczema is a prevalent chronic condition observed globally, particularly in Western industrialized nations where its prevalence is estimated to range from 2.5% to 3.5% in adults and 10% to 15% among children. The increasing incidence of atopic eczema in industrialized countries over recent decades suggests that this trend may be due to environmental changes rather than genetic predispositions. Therefore, by thoroughly examining environmental factors and their role in atopic dermatitis, one may be able to gain a better understanding of its disease pattern and develop possible preventative measures. This article provides a comprehensive analysis of how the surrounding environment contributes to the pathogenesis of atopic eczema.