通过傅立叶分析实现群体级任务诱发功能连接。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-03-14 eCollection Date: 2024-08-01 DOI:10.1093/jrsssc/qlae015

Kun Meng, Ani Eloyan

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引用次数: 0

摘要

功能磁共振成像（fMRI）是一种无创的体内成像技术，对测量大脑活动至关重要。功能连通性可用于研究大脑区域之间的关联，研究对象可在执行任务时或休息时进行研究。在本文中，我们提出了任务诱发的群体水平功能连通性（ptFC）的严格定义。重要的是，我们提出的ptFC可以在任务-MRI研究中进行解释。我们还提供了一种估算 ptFC 的算法。我们通过模拟展示了所提算法与现有功能连通性框架的性能比较。最后，我们在人类连接组计划的一项运动任务研究中应用了所提出的算法来估计ptFC。

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Population-level task-evoked functional connectivity via Fourier analysis.

Functional magnetic resonance imaging (fMRI) is a noninvasive and in-vivo imaging technique essential for measuring brain activity. Functional connectivity is used to study associations between brain regions, either while study subjects perform tasks or during periods of rest. In this paper, we propose a rigorous definition of task-evoked functional connectivity at the population level (ptFC). Importantly, our proposed ptFC is interpretable in the context of task-fMRI studies. An algorithm for estimating the ptFC is provided. We present the performance of the proposed algorithm compared to existing functional connectivity frameworks using simulations. Lastly, we apply the proposed algorithm to estimate the ptFC in a motor-task study from the Human Connectome Project.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.