{"title":"甲壳动物在将 GABA 确立为神经递质方面发挥了主要作用。","authors":"Edward A Kravitz , Saheli Sengupta","doi":"10.1016/j.cois.2024.101252","DOIUrl":null,"url":null,"abstract":"<div><p>Crustaceans played a major role in establishing that gamma-aminobutyric acid (GABA) functioned as an inhibitory transmitter compound. In fact, it is now widely accepted that GABA is the major inhibitory transmitter compound in all animal species where it has been examined. The story of its acceptance as a neurotransmitter, however, is more interesting than that. GABA was first isolated from mammalian brains by three laboratories in 1950. Great excitement surrounded this discovery, and many laboratories began exploring its function. This excitement peaked at two large international congresses in the United States at the end of the first decade of study, where a consensus of major figures in the field was that GABA was not a transmitter compound. How could this have happened?</p></div>","PeriodicalId":11038,"journal":{"name":"Current opinion in insect science","volume":"65 ","pages":"Article 101252"},"PeriodicalIF":5.8000,"publicationDate":"2024-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Crustaceans played a primary role in establishing gamma-aminobutyric acid as a neurotransmitter\",\"authors\":\"Edward A Kravitz , Saheli Sengupta\",\"doi\":\"10.1016/j.cois.2024.101252\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Crustaceans played a major role in establishing that gamma-aminobutyric acid (GABA) functioned as an inhibitory transmitter compound. In fact, it is now widely accepted that GABA is the major inhibitory transmitter compound in all animal species where it has been examined. The story of its acceptance as a neurotransmitter, however, is more interesting than that. GABA was first isolated from mammalian brains by three laboratories in 1950. Great excitement surrounded this discovery, and many laboratories began exploring its function. This excitement peaked at two large international congresses in the United States at the end of the first decade of study, where a consensus of major figures in the field was that GABA was not a transmitter compound. How could this have happened?</p></div>\",\"PeriodicalId\":11038,\"journal\":{\"name\":\"Current opinion in insect science\",\"volume\":\"65 \",\"pages\":\"Article 101252\"},\"PeriodicalIF\":5.8000,\"publicationDate\":\"2024-08-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current opinion in insect science\",\"FirstCategoryId\":\"97\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2214574524000944\",\"RegionNum\":1,\"RegionCategory\":\"农林科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current opinion in insect science","FirstCategoryId":"97","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2214574524000944","RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOLOGY","Score":null,"Total":0}
Crustaceans played a primary role in establishing gamma-aminobutyric acid as a neurotransmitter
Crustaceans played a major role in establishing that gamma-aminobutyric acid (GABA) functioned as an inhibitory transmitter compound. In fact, it is now widely accepted that GABA is the major inhibitory transmitter compound in all animal species where it has been examined. The story of its acceptance as a neurotransmitter, however, is more interesting than that. GABA was first isolated from mammalian brains by three laboratories in 1950. Great excitement surrounded this discovery, and many laboratories began exploring its function. This excitement peaked at two large international congresses in the United States at the end of the first decade of study, where a consensus of major figures in the field was that GABA was not a transmitter compound. How could this have happened?
期刊介绍：
Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year.
The following 11 areas are covered by Current Opinion in Insect Science.
-Ecology
-Insect genomics
-Global Change Biology
-Molecular Physiology (Including Immunity)
-Pests and Resistance
-Parasites, Parasitoids and Biological Control
-Behavioural Ecology
-Development and Regulation
-Social Insects
-Neuroscience
-Vectors and Medical and Veterinary Entomology
There is also a section that changes every year to reflect hot topics in the field.
Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.
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