血压变化是导管消融术后阵发性心房颤动复发的风险因素。

IF 2.2 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Journal of Arrhythmia Pub Date : 2024-06-23 DOI:10.1002/joa3.13094

Minoru Yambe MD, PhD, Yuki Kurose MD, Kaoru Hasegawa MD, PhD, Hisashi Kikuta MD, Takenori Sumiyoshi MD, PhD, Yuko Sekiguchi MD, PhD, Takeyoshi Kameyama MD, PhD, Tatsuya Komaru MD, PhD, Koji Kumagai MD, PhD

{"title":"血压变化是导管消融术后阵发性心房颤动复发的风险因素。","authors":"Minoru Yambe MD, PhD, Yuki Kurose MD, Kaoru Hasegawa MD, PhD, Hisashi Kikuta MD, Takenori Sumiyoshi MD, PhD, Yuko Sekiguchi MD, PhD, Takeyoshi Kameyama MD, PhD, Tatsuya Komaru MD, PhD, Koji Kumagai MD, PhD","doi":"10.1002/joa3.13094","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Blood pressure variability has been found to be a predictor of a stroke, heart failure, and ischemic heart disease that is independent of blood pressure control. This study used the variability independent of the mean (VIM) to evaluate the visit-to-visit blood pressure variability in patients previously undergoing catheter ablation (CA) of paroxysmal atrial fibrillation (PAF), and its relationship with AF recurrence was examined.</p>\n </section>\n \n <section>\n \n <h3> Method and Results</h3>\n \n <p>The subjects were 274 consecutive PAF patients who underwent CA at our hospital. Finally, 237 subjects were included in the analysis. The mean follow-up period was 29.6 months, during which 37 subjects had recurrences, and 200 did not. During the outpatient blood pressure examinations, the VIM of the systolic blood pressure (VIM SBP) was significantly higher in the recurrence group, suggesting that blood pressure variability is associated with recurrence. The Cox proportional hazards ratio of the VIM SBP was significantly higher in the recurrence (4.839) than no-recurrence group, even after an adjustment, suggesting that the extent of the variability was a risk factor of recurrence post-CA. In addition, the Cox proportional hazard ratio for recurrence was significantly lower in the patients taking dihydropyridine calcium channel blockers, suggesting that the risk of recurrence may differ depending on the type of antihypertensive drug.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>Blood pressure variability may be a risk for AF recurrence after CA.</p>\n </section>\n </div>","PeriodicalId":15174,"journal":{"name":"Journal of Arrhythmia","volume":"40 4","pages":"858-866"},"PeriodicalIF":2.2000,"publicationDate":"2024-06-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317737/pdf/","citationCount":"0","resultStr":"{\"title\":\"Blood pressure variability as a risk factor of recurrent paroxysmal atrial fibrillation after catheter ablation\",\"authors\":\"Minoru Yambe MD, PhD, Yuki Kurose MD, Kaoru Hasegawa MD, PhD, Hisashi Kikuta MD, Takenori Sumiyoshi MD, PhD, Yuko Sekiguchi MD, PhD, Takeyoshi Kameyama MD, PhD, Tatsuya Komaru MD, PhD, Koji Kumagai MD, PhD\",\"doi\":\"10.1002/joa3.13094\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Blood pressure variability has been found to be a predictor of a stroke, heart failure, and ischemic heart disease that is independent of blood pressure control. This study used the variability independent of the mean (VIM) to evaluate the visit-to-visit blood pressure variability in patients previously undergoing catheter ablation (CA) of paroxysmal atrial fibrillation (PAF), and its relationship with AF recurrence was examined.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Method and Results</h3>\\n \\n <p>The subjects were 274 consecutive PAF patients who underwent CA at our hospital. Finally, 237 subjects were included in the analysis. The mean follow-up period was 29.6 months, during which 37 subjects had recurrences, and 200 did not. During the outpatient blood pressure examinations, the VIM of the systolic blood pressure (VIM SBP) was significantly higher in the recurrence group, suggesting that blood pressure variability is associated with recurrence. The Cox proportional hazards ratio of the VIM SBP was significantly higher in the recurrence (4.839) than no-recurrence group, even after an adjustment, suggesting that the extent of the variability was a risk factor of recurrence post-CA. In addition, the Cox proportional hazard ratio for recurrence was significantly lower in the patients taking dihydropyridine calcium channel blockers, suggesting that the risk of recurrence may differ depending on the type of antihypertensive drug.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>Blood pressure variability may be a risk for AF recurrence after CA.</p>\\n </section>\\n </div>\",\"PeriodicalId\":15174,\"journal\":{\"name\":\"Journal of Arrhythmia\",\"volume\":\"40 4\",\"pages\":\"858-866\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2024-06-23\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11317737/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Arrhythmia\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/joa3.13094\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CARDIAC & CARDIOVASCULAR SYSTEMS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Arrhythmia","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/joa3.13094","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}

引用次数: 0

摘要

背景：研究发现，血压变异性是中风、心力衰竭和缺血性心脏病的预测因素，与血压控制无关。本研究使用独立于平均值的变异性（VIM）来评估曾接受阵发性心房颤动（PAF）导管消融术（CA）的患者每次就诊时的血压变异性，并研究其与房颤复发的关系：研究对象为在我院接受导管消融术的连续 274 例 PAF 患者。最后，237 名受试者被纳入分析。平均随访时间为 29.6 个月，其中 37 人复发，200 人未复发。在门诊血压检查中，复发组的收缩压VIM（VIM SBP）明显高于复发组，这表明血压变化与复发有关。即使经过调整，复发组 VIM 收缩压的 Cox 比例危险比（4.839）也明显高于未复发组，这表明血压变异的程度是冠状动脉造影术后复发的一个危险因素。此外，服用二氢吡啶类钙通道阻滞剂的患者复发的Cox比例危险比明显降低，这表明不同类型的降压药物可能会导致不同的复发风险：结论：血压变化可能是 CA 后房颤复发的一个风险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Blood pressure variability as a risk factor of recurrent paroxysmal atrial fibrillation after catheter ablation

查看原文本刊更多论文

Blood pressure variability as a risk factor of recurrent paroxysmal atrial fibrillation after catheter ablation

Background

Blood pressure variability has been found to be a predictor of a stroke, heart failure, and ischemic heart disease that is independent of blood pressure control. This study used the variability independent of the mean (VIM) to evaluate the visit-to-visit blood pressure variability in patients previously undergoing catheter ablation (CA) of paroxysmal atrial fibrillation (PAF), and its relationship with AF recurrence was examined.

Method and Results

The subjects were 274 consecutive PAF patients who underwent CA at our hospital. Finally, 237 subjects were included in the analysis. The mean follow-up period was 29.6 months, during which 37 subjects had recurrences, and 200 did not. During the outpatient blood pressure examinations, the VIM of the systolic blood pressure (VIM SBP) was significantly higher in the recurrence group, suggesting that blood pressure variability is associated with recurrence. The Cox proportional hazards ratio of the VIM SBP was significantly higher in the recurrence (4.839) than no-recurrence group, even after an adjustment, suggesting that the extent of the variability was a risk factor of recurrence post-CA. In addition, the Cox proportional hazard ratio for recurrence was significantly lower in the patients taking dihydropyridine calcium channel blockers, suggesting that the risk of recurrence may differ depending on the type of antihypertensive drug.