A Martini, A Ravelli, S Viola, P De Stefano, C Borgna
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Hypergammaglobulinemic purpura in childhood. Report of two cases and review of the literature.
Hypergammaglobulinemic purpura is a rare syndrome characterized by long-standing recurrent purpura of the lower limbs, polyclonal hypergammaglobulinemia, increased erythrocyte sedimentation rate and high titer rheumatoid factor positivity. The syndrome can occur isolated or in association with a systemic disease. Few cases have been described in childhood. We report two cases together with a review of the paediatric literature.
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