恶性胆道梗阻中的经皮金属支架:镍钛诺支架与壁式支架的比较

IF 1.6 Q4 ONCOLOGY
Journal of Gastrointestinal Cancer Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI:10.1007/s12029-024-01101-y
İlker Özgür Koska, Devrim Akıncı, Okan Akhan
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引用次数: 0

摘要

导言:缓解恶性胆道梗阻非常重要,通常采用经皮胆道支架置入术。本研究的主要目的是评估壁式支架和镍钛诺支架在缓解恶性胆道梗阻方面的性能:方法:我们对 1995 年 1 月 1 日至 2005 年 12 月 31 日期间在我科接受胆道支架手术的 157 名患者的病历进行了回顾性分析。对所有患者的技术成功率、治疗成功率、前 30 天的死亡率、轻微并发症和主要并发症进行了评估和比较,并将其作为主要研究终点。此外,还对可获得随访信息的患者的支架通畅率和支架植入后的平均存活时间进行了评估:共为 157 名患者植入了 213 个金属支架。其中 83 名患者植入了壁式支架,平均年龄为 60.4 岁,平均标码为 13.5。镍钛诺支架植入了 74 例患者,平均年龄为 57.8 岁,标准差为 15.5。两组患者的性别比例相同。在整个研究期间,镍钛诺支架组和壁式支架组各有 13 名患者出现胆道支架功能障碍。再闭塞率没有统计学差异(P = 0.91)。镍钛诺支架组的中位初次通畅时间为 119 天(90-185 天,CI 95%),壁式支架组的中位初次通畅时间为 81 天(60-150 天,CI 95%):镍钛诺支架和壁式支架是经皮治疗恶性胆道梗阻的安全选择,具有相似的治疗效果和治疗成功率,并发症发生率低,通畅时间可超过预期生存时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Percutaneous Metallic Stents in Malignant Biliary Obstruction: Comparison of Nitinol and Wall Stents.

Introduction: Palliation of malign biliary obstruction is important which is commonly carried out by percutaneous biliary stenting. Our primary aim with this study was assessment of performance of wall stents, and nitinol stents for the palliation of malign biliary obstruction.

Methods: The medical records of 157 patients who underwent biliary stenting in our department between January 1, 1995, and December 31, 2005, were retrospectively analyzed. Technical success, treatment success, mortality in the first 30 days, minor, and major complications were evaluated and compared among the wall stent, and the nitinol stent groups in all patients which constituted the primary study endpoints. Additionally, stent patency, and mean patient survival times after stent implantation were evaluated in patients for whom follow-up information could be obtained.

Results: A total of 213 metallic stents were placed in 157 patients. Wall stent was placed in 83 of the patients with mean age, and SD of 60.4 and 13.5. Nitinol stent was placed in 74 of the patients with mean age of 57.8, and SD of 15.5. Gender ratio was equal in both groups. Biliary stent dysfunction was observed in 13 patients in each of nitinol, and wall stent groups throughout the study period. There was no statistical difference among re-occlusion rates (p = 0.91). For the nitinol stent group median primary patency time was 119 days (90-185 days CI 95%), and for the wall stent group median primary patency time was 81 days (60-150 days CI 95%).

Conclusion: Nitinol stents, and wall stents are safe options that can be safely used in the percutaneous treatment of malignant biliary obstruction with similar treatment and therapeutic success, low complication rates, and patency times that can extend beyond expected survival times.

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来源期刊
CiteScore
3.80
自引率
0.00%
发文量
121
期刊介绍: The Journal of Gastrointestinal Cancer is a multidisciplinary medium for the publication of novel research pertaining to cancers arising from the gastrointestinal tract.The journal is dedicated to the most rapid publication possible.The journal publishes papers in all relevant fields, emphasizing those studies that are helpful in understanding and treating cancers affecting the esophagus, stomach, liver, gallbladder and biliary tree, pancreas, small bowel, large bowel, rectum, and anus. In addition, the Journal of Gastrointestinal Cancer publishes basic and translational scientific information from studies providing insight into the etiology and progression of cancers affecting these organs. New insights are provided from diverse areas of research such as studies exploring pre-neoplastic states, risk factors, epidemiology, genetics, preclinical therapeutics, surgery, radiation therapy, novel medical therapeutics, clinical trials, and outcome studies.In addition to reports of original clinical and experimental studies, the journal also publishes: case reports, state-of-the-art reviews on topics of immediate interest or importance; invited articles analyzing particular areas of pancreatic research and knowledge; perspectives in which critical evaluation and conflicting opinions about current topics may be expressed; meeting highlights that summarize important points presented at recent meetings; abstracts of symposia and conferences; book reviews; hypotheses; Letters to the Editors; and other items of special interest, including:Complex Cases in GI Oncology:  This is a new initiative to provide a forum to review and discuss the history and management of complex and involved gastrointestinal oncology cases. The format will be similar to a teaching case conference where a case vignette is presented and is followed by a series of questions and discussion points. A brief reference list supporting the points made in discussion would be expected.
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