低容量高强度间歇训练 (LV-HIIT) 对 2 型糖尿病 (T2DM) 患者脂肪肝指数 (FLI) 和估计肾小球滤过率 (eGFR) 的影响。

IF 2.4 Q3 ENDOCRINOLOGY & METABOLISM
Rasoul Raesi, Saeid Kalbasi, Abbas Ali Gaeini, Maryam Haji Ghasem Kashani, Khadijeh Tajik
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引用次数: 0

摘要

背景:目的:本研究旨在确定低容量高强度间歇训练(LV-HIIT)对 T2DM 患者脂肪肝指数(FLI)和 GFR 估计值的影响:这项随机对照试验包括80名T2DM患者和久坐不动的生活方式,随机分为HIIT组(40人)和对照组(40人)。患者均有至少一年的 T2DM 病史,HbA1C 水平在 6.4% 至 10% 之间。干预组接受为期 4 周的 LV-HIIT 训练,每周 3 次,对照组不接受任何干预。在干预前后,对所有参与者的 FLI、eGFR、人体测量和实验室变量进行了评估:结果:干预后,左心室-HIIT 组的 FLI(基线为 62.0,随访时为 53.0)显著下降,而 eGFR(基线为 71.0,随访时为 73.6)显著上升(结论:左心室-HIIT 运动似乎是一种有效的减肥方法:左心室-HIIT运动似乎是改善T2DM患者FLI和eGFR的有效训练方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of Low-Volume High-Intensity Interval Training (LV-HIIT) on Fatty Liver Index (FLI) and Estimated Glomerular Filtration Rate (eGFR) in Patients with Type 2 Diabetes Mellitus (T2DM).

Background: Prevention and reduction of liver fat accumulation and maintenance of Glomerular Filtration Rate (GFR) have been proposed as important therapeutic goals in patients with Type 2 Diabetes Mellitus (T2DM).

Aim: This study aimed to determine the effect of Low-Volume High-Intensity Interval Training (LV-HIIT) on fatty liver index (FLI) and GFR estimation in patients with T2DM.

Methods: This randomized controlled trial included 80 patients with T2DM and a sedentary lifestyle, randomly divided into HIIT (n=40) and a control group (n=40). Patients with a history of T2DM for at least one year and HbA1C levels between 6.4% and 10% were selected. The intervention group underwent a 4-week LV-HIIT course, comprising 3 sessions per week, while the control group did not receive any intervention. FLI, eGFR, anthropometric measurements, and laboratory variables were assessed in all participants before and after the intervention.

Results: FLI (62.0 at baseline, 53.0 at follow-up) significantly decreased in the LV-HIIT group after the intervention, while eGFR (71.0 at baseline, 73.6 at follow-up) significantly increased (P<0.001). However, the control group showed a significant reduction only in Fasting Blood Sugar (FBS) (P<0.05). After the intervention, the LV-HIIT group had significantly lower FBS (129.0 at baseline, 121.0 at follow-up), Alanine Aminotransferase (ALT) (24.0 at baseline, 18.0 at follow-up), and Gamma-Glutamyl Transferase (GGT) (22.0 at baseline, 19.0 at follow-up), as well as higher eGFR, compared to the control group (P<0.05).

Conclusions: LV-HIIT exercise appears to be a promising and effective training method for improving FLI and eGFR in patients diagnosed with T2DM.

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来源期刊
Current diabetes reviews
Current diabetes reviews ENDOCRINOLOGY & METABOLISM-
CiteScore
6.30
自引率
0.00%
发文量
158
期刊介绍: Current Diabetes Reviews publishes frontier reviews on all the latest advances on diabetes and its related areas e.g. pharmacology, pathogenesis, complications, epidemiology, clinical care, and therapy. The journal"s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all researchers and clinicians who are involved in the field of diabetes.
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