A. González-García , M. Fabregate , G. Serralta , B. de Miguel Campo , A. Noblejas Mozo , Á. Robles-Marhuenda , en representación de la Sección de Autoinmunes de la Sociedad de Medicina Interna Madrid-Castilla La Mancha
{"title":"18F-FDG-PET/CT在检测多发性风湿痛或巨细胞动脉炎患者颅外大血管炎中的作用：系统综述和荟萃分析。","authors":"A. González-García , M. Fabregate , G. Serralta , B. de Miguel Campo , A. Noblejas Mozo , Á. Robles-Marhuenda , en representación de la Sección de Autoinmunes de la Sociedad de Medicina Interna Madrid-Castilla La Mancha","doi":"10.1016/j.rce.2024.04.016","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Systematic review of current evidence to analyze the prevalence of extracranial large vessel vasculitis (LVV) using <sup>18</sup>F-FDG PET/CT in patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA).</p></div><div><h3>Materials and methods</h3><p>PubMed and EMBASE were searched and the results were screened by two reviewers. Study quality was assessed using a modified version of the Newcastle-Ottawa scale. Heterogeneity between studies was assessed using the I<sup>2</sup> statistic and the Q test. Further subgroup analyses were performed by disease type, study quality, and <sup>18</sup>F-FDG PET/CT uptake criteria. Publication bias was assessed by funnel plot and Egger's test.</p></div><div><h3>Results</h3><p>268 publications were identified, of which 17 met the selection criteria and were included in the meta-analysis. The overall pooled prevalence of extracranial VGV by <sup>18</sup>F-FDG PET/CT was 54.5% [95% CI: 42.6% to 66.1%]. In patients with GCA the prevalence was significantly higher than in patients with PMR (60.1% vs. 41.8%, <em>P</em>= .006). Likewise, studies with a lower risk of bias reported a higher prevalence of extracranial VGV (61.1% vs. 46.9%; <em>P</em>= .010). No publication bias was observed.</p></div><div><h3>Conclusions</h3><p>The <sup>18</sup>F-FDGPET/CT test may be useful in the detection of extracranial VGV, both in patients with PMR or GCA. Such involvement is more frequent in patients with GCA, and may vary depending on the quality of the studies.</p></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"224 7","pages":"Pages 445-456"},"PeriodicalIF":2.3000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Utilidad del 18F-FDG-PET/TC en la detección de vasculitis de gran vaso extracraneal en pacientes con polimialgia reumática o arteritis de células gigantes: revisión sistemática y metaanálisis\",\"authors\":\"A. González-García , M. Fabregate , G. Serralta , B. de Miguel Campo , A. Noblejas Mozo , Á. Robles-Marhuenda , en representación de la Sección de Autoinmunes de la Sociedad de Medicina Interna Madrid-Castilla La Mancha\",\"doi\":\"10.1016/j.rce.2024.04.016\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Systematic review of current evidence to analyze the prevalence of extracranial large vessel vasculitis (LVV) using <sup>18</sup>F-FDG PET/CT in patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA).</p></div><div><h3>Materials and methods</h3><p>PubMed and EMBASE were searched and the results were screened by two reviewers. Study quality was assessed using a modified version of the Newcastle-Ottawa scale. Heterogeneity between studies was assessed using the I<sup>2</sup> statistic and the Q test. Further subgroup analyses were performed by disease type, study quality, and <sup>18</sup>F-FDG PET/CT uptake criteria. Publication bias was assessed by funnel plot and Egger's test.</p></div><div><h3>Results</h3><p>268 publications were identified, of which 17 met the selection criteria and were included in the meta-analysis. The overall pooled prevalence of extracranial VGV by <sup>18</sup>F-FDG PET/CT was 54.5% [95% CI: 42.6% to 66.1%]. In patients with GCA the prevalence was significantly higher than in patients with PMR (60.1% vs. 41.8%, <em>P</em>= .006). Likewise, studies with a lower risk of bias reported a higher prevalence of extracranial VGV (61.1% vs. 46.9%; <em>P</em>= .010). No publication bias was observed.</p></div><div><h3>Conclusions</h3><p>The <sup>18</sup>F-FDGPET/CT test may be useful in the detection of extracranial VGV, both in patients with PMR or GCA. Such involvement is more frequent in patients with GCA, and may vary depending on the quality of the studies.</p></div>\",\"PeriodicalId\":21223,\"journal\":{\"name\":\"Revista clinica espanola\",\"volume\":\"224 7\",\"pages\":\"Pages 445-456\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista clinica espanola\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0014256524001103\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista clinica espanola","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014256524001103","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Utilidad del 18F-FDG-PET/TC en la detección de vasculitis de gran vaso extracraneal en pacientes con polimialgia reumática o arteritis de células gigantes: revisión sistemática y metaanálisis
Objective
Systematic review of current evidence to analyze the prevalence of extracranial large vessel vasculitis (LVV) using 18F-FDG PET/CT in patients with polymyalgia rheumatica (PMR) or giant cell arteritis (GCA).
Materials and methods
PubMed and EMBASE were searched and the results were screened by two reviewers. Study quality was assessed using a modified version of the Newcastle-Ottawa scale. Heterogeneity between studies was assessed using the I2 statistic and the Q test. Further subgroup analyses were performed by disease type, study quality, and 18F-FDG PET/CT uptake criteria. Publication bias was assessed by funnel plot and Egger's test.
Results
268 publications were identified, of which 17 met the selection criteria and were included in the meta-analysis. The overall pooled prevalence of extracranial VGV by 18F-FDG PET/CT was 54.5% [95% CI: 42.6% to 66.1%]. In patients with GCA the prevalence was significantly higher than in patients with PMR (60.1% vs. 41.8%, P= .006). Likewise, studies with a lower risk of bias reported a higher prevalence of extracranial VGV (61.1% vs. 46.9%; P= .010). No publication bias was observed.
Conclusions
The 18F-FDGPET/CT test may be useful in the detection of extracranial VGV, both in patients with PMR or GCA. Such involvement is more frequent in patients with GCA, and may vary depending on the quality of the studies.
期刊介绍：
Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.
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