Achraf Abdou, Fatima Ezzahra Maaghloud, Nikolay Tumanov, Johan Wouters, Jamal JamalEddine, Abdelhakim Elmakssoudi, Mohamed Dakir
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Oxidation of Eugenol Derivatives with KMnO4 and CrO3
This study aims to delineate the synthesis of eugenol derivatives, starting with hydroxyl group protection and then the subsequent oxidation stages. Initially, eugenol underwent conversion into acetyleugenol and benzyleugenol during the protection phase. Subsequently, a kinetic oxidation of acetyleugenol with KMnO4 via GC-MS analysis resulted in the identification of four compounds. The kinetic investigation indicated the primary formation of diolacetyleugenol, succeeded by aldehyde eugenol, which further gets converted into its respective carboxylic acid. Additionally, acetyleugenol and benzyleugenol underwent oxidation with CrO3, yielding the corresponding carboxylic acids.
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