恶性外耳道炎:持续的挑战

Q3 Medicine
Mayssa Khribi, Wed El Abed, Khalil Gnaba
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引用次数: 0

摘要

简介恶性外耳道炎虽然罕见,但发病率很高,有时甚至致命。目的:分析恶性外耳道炎的临床、微生物学和放射学特征以及治疗方法:2013年1月至2021年8月,凯鲁万医院耳鼻喉科对38名因恶性外耳道炎住院治疗的患者进行了描述性横断面研究:患者的平均年龄为 67.7 ± 12.9 岁(35-98 岁)。所有患者均表现为持续性耳痛,常用止痛药无效。76.3%的病例出现耳痛,2例(5.3%)出现面瘫,1例(2.6%)出现发音障碍。绿脓杆菌是主要病原体(42%)。6.4%的病例合并细菌和真菌感染。一线静脉抗生素治疗主要使用头孢菌素类和氟喹诺酮类药物。30名患者(79%)的病情完全缓解。然而,在我们的系列治疗中,有 8 例复发(21%)和 2 例死亡(5.2%)。平均随访时间为 4.6±6.3(1-26 个月):结论:绿脓杆菌仍是恶性外耳道炎的主要病原体。结论:绿脓杆菌仍是恶性外耳道炎的主要病原体,但由于抗生素的过度使用,真菌感染也在不断增加。抗生素疗法应根据培养结果和医院病原体的耐药性情况进行调整。从业人员应注意并发真菌感染的可能性,尤其是在病情恶化的情况下。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Malignant Otitis Externa: A persistent challenge.

Introduction: Although rare, Malignant otitis externa is responsible for a high morbidity and could sometimes be fatal. The management of this condition is still challenging.

Aim: To analyse the clinical, microbiological and radiological profile of malignant otitis externa, and the management of this condition.

Methods: A descriptive, cross-sectional study was conducted at ENT Department of Kairouan's hospital including 38 patients hospitalised and treated for malignant otitis externa from January 2013 to August 2021.

Results: The mean age of patients was 67.7 ± 12.9 years (35-98). All patients presented with continuous otalgia that resists to usual analgesics. Otorrhea was noticed in 76.3% of cases, facial palsy in 2 cases (5.3%) and dysphonia in one case (2.6%). Pseudomonas Aeruginosa was the main responsible pathogen (42%). Concomitant bacterial and fungal infection was noticed in 6.4% of the cases. First-line intravenous antibiotherapy used was mainly based on an association of Cephalosporins and Fluoroquinolones. Complete remission was noticed in 30 patients (79%). However, 8 cases of recurrences (21%) and 2 cases of deaths (5.2%) were noticed in our series. The mean follow-up was 4.6±6.3 (1-26 months).

Conclusions: Pseudomonas Aeruginosa remains the main responsible pathogen for malignant otitis externa. Nevertheless, fungal infections are rising because of the overuse of antibiotics. Antibiotherapy should be adapted to culture results and resistance profile of pathogens in hospital. Practionners should be aware of the possibility of concomitant fungal infection, especially in the case of unfavorable evolution.

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来源期刊
Tunisie Medicale
Tunisie Medicale Medicine-Medicine (all)
CiteScore
1.00
自引率
0.00%
发文量
72
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