双病因 MAFLD:病毒性乙型肝炎、病毒性丙型肝炎、酒精和 MAFLD 之间的相互作用。

IF 5.9 2区 医学 Q1 GASTROENTEROLOGY & HEPATOLOGY
Hepatology International Pub Date : 2024-10-01 Epub Date: 2024-08-08 DOI:10.1007/s12072-024-10699-x
Chun-Jen Liu, Wai Kay Seto, Ming-Lung Yu
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引用次数: 0

摘要

代谢功能障碍相关性脂肪肝(MAFLD)和慢性乙型肝炎病毒(HBV)或丙型肝炎病毒(HCV)感染引起的病毒性肝炎是全球常见的肝病。过度饮酒和酒精性肝病(ALD)也是新出现的健康问题。因此,在临床实践中,我们可能会遇到双重病因的肝病患者,如并存 MAFLD/HBV、MAFLD/HCV 和 MAFLD/ALD。在这篇综述中,我们总结了MAFLD与同时存在的HBV、HCV或ALD的流行病学、临床特征和相互影响。我们还讨论了MAFLD对慢性病毒性肝炎患者肝病进展和治疗效果的影响,以及需要解决的有关双重MAFLD和ALD的临床问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD.

Dual-etiology MAFLD: the interactions between viral hepatitis B, viral hepatitis C, alcohol, and MAFLD.

Metabolic dysfunction-associated fatty liver disease (MAFLD) and viral hepatitis due to chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) infection are common liver diseases worldwide. Excessive alcohol consumption and alcoholic liver disease (ALD) are also emerging health problems. Therefore, in clinical practice, we may encounter subjects with dual etiology of liver diseases such as coexisting MAFLD/HBV, MAFLD/HCV, and MAFLD/ALD. In this review, we summarize the epidemiology, clinical features, and mutual interactions of MAFLD with coexisting HBV, HCV, or ALD. The impact of MAFLD on the progression of liver diseases and treatment outcomes in patients with chronic viral hepatitis and the clinical questions to be addressed regarding dual MAFLD and ALD are also discussed.

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来源期刊
Hepatology International
Hepatology International 医学-胃肠肝病学
CiteScore
10.90
自引率
3.00%
发文量
167
审稿时长
6-12 weeks
期刊介绍: Hepatology International is the official journal of the Asian Pacific Association for the Study of the Liver (APASL). This is a peer-reviewed journal featuring articles written by clinicians, clinical researchers and basic scientists is dedicated to research and patient care issues in hepatology. This journal will focus mainly on new and emerging technologies, cutting-edge science and advances in liver and biliary disorders. Types of articles published: -Original Research Articles related to clinical care and basic research -Review Articles -Consensus guidelines for diagnosis and treatment -Clinical cases, images -Selected Author Summaries -Video Submissions
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