Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas
{"title":"甲胎蛋白造影健康评分:异维A酸引起的寻常型痤疮患者甲胎蛋白造影改变的简单分级系统。","authors":"Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas","doi":"10.5935/0004-2749.2023-0150","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.</p><p><strong>Methods: </strong>After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named \"meibography health score.\" The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.</p><p><strong>Results: </strong>The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.</p><p><strong>Conclusion: </strong>The meibography health score exhibited good interrater reliability, particularly in severe cases.</p>","PeriodicalId":8397,"journal":{"name":"Arquivos brasileiros de oftalmologia","volume":"88 1","pages":"e20230150"},"PeriodicalIF":1.1000,"publicationDate":"2024-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris.\",\"authors\":\"Fabio Mendonça Xavier Andrade, Flavio Hirai, Tais Hitomi Wakamatsu, Rebecca Ignacio Subira Medina, Denise de Freitas\",\"doi\":\"10.5935/0004-2749.2023-0150\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.</p><p><strong>Methods: </strong>After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named \\\"meibography health score.\\\" The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.</p><p><strong>Results: </strong>The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.</p><p><strong>Conclusion: </strong>The meibography health score exhibited good interrater reliability, particularly in severe cases.</p>\",\"PeriodicalId\":8397,\"journal\":{\"name\":\"Arquivos brasileiros de oftalmologia\",\"volume\":\"88 1\",\"pages\":\"e20230150\"},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2024-08-02\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Arquivos brasileiros de oftalmologia\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.5935/0004-2749.2023-0150\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Arquivos brasileiros de oftalmologia","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.5935/0004-2749.2023-0150","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Meibography health score: a simple grading system for isotretinoin-induced meibography alterations on patients with acne vulgaris.
Purpose: To develop a simple, subjective, and reliable grading scale for isotretinoin-induced meibography changes.
Methods: After analyzing meibography images obtained from systemic isotretinoin users, a grading scale was proposed and named "meibography health score." The score ranged from 1 to 3, with decreasing gland reflectivity and identifiable margins. A total of 11 medical professionals were asked to grade 10 meibography images obtained from isotretinoin users using the proposed scale and were divided into three groups: (A) ophthalmologists with experience with meibography, (B) ophthalmologists with no experience with meibography, and (C) radiologists. The kappa statistic was determined to test interrater reliability.
Results: The overall kappa was approximately 0.64. The kappa scores for Groups A, B, and C were 0.78, 0.59, and 0.90, respectively. Grade 2 had the lowest kappa scores (0.62, 0.35, and 0.82 for A, B, and C, respectively) and grade 3 the highest (0.78, 0.90, and 1.0 for A, B and C, respectively). Furthermore, Group C had the highest kappa scores and Group B the lowest.
Conclusion: The meibography health score exhibited good interrater reliability, particularly in severe cases.
期刊介绍:
The ABO-ARQUIVOS BRASILEIROS DE OFTALMOLOGIA (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - (ABO, ISSN 0004-2749 - print and ISSN 1678-2925 - electronic version), the official bimonthly publication of the Brazilian Council of Ophthalmology (CBO), aims to disseminate scientific studies in Ophthalmology, Visual Science and Health public, by promoting research, improvement and updating of professionals related to the field.