Anders Peder Højer Karlsen, Pernille Bjersand Sunde, Markus Harboe Olsen, Jens Laigaard, Caroline Folkersen, Trang Xuan Minh Tran, Ida Houtved Rasmussen, Selma Kjartansdóttir, Atena Saito, Michael Asger Andersen, Mathias Maagaard, Nicholas Papadomanolakis-Pakis, Kim Dalhoff, Lone Nikolajsen, Troels Haxholdt Lunn, Christian Sylvest Meyhoff, Janus Christian Jakobsen, Ole Mathiesen
{"title":"围术期阿片类药物和个性化镇痛：五项系统性综述方案。","authors":"Anders Peder Højer Karlsen, Pernille Bjersand Sunde, Markus Harboe Olsen, Jens Laigaard, Caroline Folkersen, Trang Xuan Minh Tran, Ida Houtved Rasmussen, Selma Kjartansdóttir, Atena Saito, Michael Asger Andersen, Mathias Maagaard, Nicholas Papadomanolakis-Pakis, Kim Dalhoff, Lone Nikolajsen, Troels Haxholdt Lunn, Christian Sylvest Meyhoff, Janus Christian Jakobsen, Ole Mathiesen","doi":"10.1111/aas.14508","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Treatment with opioids is a mainstay in perioperative pain management. While the leading treatment paradigm has been procedure-specific pain management, efforts regarding personalized pain treatment are increasing. The OPI•AID project aims to develop personalized algorithms for perioperative pain management, taking demographic, surgical, and anaesthesiologic factors into account. We will undertake five parallel reviews to illuminate current evidence on different aspects of individual responses to perioperative opioid treatment.</p><p><strong>Methods: </strong>Inclusion of adult populations in English-written studies. Review-specific searches are developed for the following databases: CENTRAL, MEDLINE, Embase, clinicaltrials.gov, and clinicaltrial.eu. Two authors will independently screen citations, extract data, and assess the risks of bias in each review (QUIPS, PROBAST and RoB2, as relevant).</p><p><strong>Conclusion: </strong>These reviews will evaluate various aspects of perioperative opioid treatment, including individualized treatment strategies, selection of specific opioids, and individual patient responses. These will guide future development of a personalized perioperative opioid treatment algorithm (OPI•AID) that will be validated and tested clinically against standard of care.</p>","PeriodicalId":6909,"journal":{"name":"Acta Anaesthesiologica Scandinavica","volume":" ","pages":"1573-1580"},"PeriodicalIF":1.9000,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews.\",\"authors\":\"Anders Peder Højer Karlsen, Pernille Bjersand Sunde, Markus Harboe Olsen, Jens Laigaard, Caroline Folkersen, Trang Xuan Minh Tran, Ida Houtved Rasmussen, Selma Kjartansdóttir, Atena Saito, Michael Asger Andersen, Mathias Maagaard, Nicholas Papadomanolakis-Pakis, Kim Dalhoff, Lone Nikolajsen, Troels Haxholdt Lunn, Christian Sylvest Meyhoff, Janus Christian Jakobsen, Ole Mathiesen\",\"doi\":\"10.1111/aas.14508\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Treatment with opioids is a mainstay in perioperative pain management. While the leading treatment paradigm has been procedure-specific pain management, efforts regarding personalized pain treatment are increasing. The OPI•AID project aims to develop personalized algorithms for perioperative pain management, taking demographic, surgical, and anaesthesiologic factors into account. We will undertake five parallel reviews to illuminate current evidence on different aspects of individual responses to perioperative opioid treatment.</p><p><strong>Methods: </strong>Inclusion of adult populations in English-written studies. Review-specific searches are developed for the following databases: CENTRAL, MEDLINE, Embase, clinicaltrials.gov, and clinicaltrial.eu. Two authors will independently screen citations, extract data, and assess the risks of bias in each review (QUIPS, PROBAST and RoB2, as relevant).</p><p><strong>Conclusion: </strong>These reviews will evaluate various aspects of perioperative opioid treatment, including individualized treatment strategies, selection of specific opioids, and individual patient responses. These will guide future development of a personalized perioperative opioid treatment algorithm (OPI•AID) that will be validated and tested clinically against standard of care.</p>\",\"PeriodicalId\":6909,\"journal\":{\"name\":\"Acta Anaesthesiologica Scandinavica\",\"volume\":\" \",\"pages\":\"1573-1580\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-11-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Acta Anaesthesiologica Scandinavica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1111/aas.14508\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/8/6 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Acta Anaesthesiologica Scandinavica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/aas.14508","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/8/6 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Opioids and personalized analgesia in the perioperative setting: A protocol for five systematic reviews.
Background: Treatment with opioids is a mainstay in perioperative pain management. While the leading treatment paradigm has been procedure-specific pain management, efforts regarding personalized pain treatment are increasing. The OPI•AID project aims to develop personalized algorithms for perioperative pain management, taking demographic, surgical, and anaesthesiologic factors into account. We will undertake five parallel reviews to illuminate current evidence on different aspects of individual responses to perioperative opioid treatment.
Methods: Inclusion of adult populations in English-written studies. Review-specific searches are developed for the following databases: CENTRAL, MEDLINE, Embase, clinicaltrials.gov, and clinicaltrial.eu. Two authors will independently screen citations, extract data, and assess the risks of bias in each review (QUIPS, PROBAST and RoB2, as relevant).
Conclusion: These reviews will evaluate various aspects of perioperative opioid treatment, including individualized treatment strategies, selection of specific opioids, and individual patient responses. These will guide future development of a personalized perioperative opioid treatment algorithm (OPI•AID) that will be validated and tested clinically against standard of care.
期刊介绍：
Acta Anaesthesiologica Scandinavica publishes papers on original work in the fields of anaesthesiology, intensive care, pain, emergency medicine, and subjects related to their basic sciences, on condition that they are contributed exclusively to this Journal. Case reports and short communications may be considered for publication if of particular interest; also letters to the Editor, especially if related to already published material. The editorial board is free to discuss the publication of reviews on current topics, the choice of which, however, is the prerogative of the board. Every effort will be made by the Editors and selected experts to expedite a critical review of manuscripts in order to ensure rapid publication of papers of a high scientific standard.
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