利用受激回波快速绘制偏置校正电导率图。

IF 2 4区 医学 Q3 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
Santhosh Iyyakkunnel, Matthias Weigel, Oliver Bieri
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引用次数: 0

摘要

目的:证明双角刺激回波(DA-STE)方法的潜力,该方法可通过同时测量 B 1 + 幅值和收发相位,快速、准确地进行基于亥姆霍兹的 "全 "同质电特性层析成像:方法:自旋回波和受激回波的组合可用于估算 B 1 + 幅值和收发相位,从而为 "全 "EPT 重建提供手段。采用交错二维采集方案进行快速采集。该方法在盐水模型中进行了验证,并与基于两次单梯度回波采集的双角度方法(GRE-DAM)进行了比较。该方法在一名健康志愿者的大脑中进行了评估:结果:使用 DA-STE 获得的 B 1 + 幅值与 GRE-DAM 方法显示出极佳的一致性。在生理盐水模型中,基于 "完整 "EPT 重建的电导率值也与预期值非常吻合。在大脑中,该方法得出的电导率值接近文献值:讨论:该方法允许使用基于 "完整 "亥姆霍兹的 EPT 重建,而无需额外的测量。因此,与基于相位的 EPT 重建相比,定量电导率值得到了改善。DA-STE 是一种快速的复合 B 1 + 绘图技术,可在 3 T 时将 EPT 应用于临床。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Fast bias-corrected conductivity mapping using stimulated echoes.

Fast bias-corrected conductivity mapping using stimulated echoes.

Objective: To demonstrate the potential of a double angle stimulated echo (DA-STE) method for fast and accurate "full" homogeneous Helmholtz-based electrical properties tomography using a simultaneous B 1 + magnitude and transceive phase measurement.

Methods: The combination of a spin and stimulated echo can be used to yield an estimate of both B 1 + magnitude and transceive phase and thus provides the means for "full" EPT reconstruction. An interleaved 2D acquisition scheme is used for rapid acquisition. The method was validated in a saline phantom and compared to a double angle method based on two single gradient echo acquisitions (GRE-DAM). The method was evaluated in the brain of a healthy volunteer.

Results: The B 1 + magnitude obtained with DA-STE showed excellent agreement with the GRE-DAM method. Conductivity values based on the "full" EPT reconstruction also agreed well with the expectations in the saline phantom. In the brain, the method delivered conductivity values close to literature values.

Discussion: The method allows the use of the "full" Helmholtz-based EPT reconstruction without the need for additional measurements. As a result, quantitative conductivity values are improved compared to phase-based EPT reconstructions. DA-STE is a fast complex- B 1 + mapping technique that could render EPT clinically relevant at 3 T.

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来源期刊
CiteScore
4.60
自引率
0.00%
发文量
58
审稿时长
>12 weeks
期刊介绍: MAGMA is a multidisciplinary international journal devoted to the publication of articles on all aspects of magnetic resonance techniques and their applications in medicine and biology. MAGMA currently publishes research papers, reviews, letters to the editor, and commentaries, six times a year. The subject areas covered by MAGMA include: advances in materials, hardware and software in magnetic resonance technology, new developments and results in research and practical applications of magnetic resonance imaging and spectroscopy related to biology and medicine, study of animal models and intact cells using magnetic resonance, reports of clinical trials on humans and clinical validation of magnetic resonance protocols.
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