慢性高碳酸血症呼吸衰竭的病理生理学。

IF 3.1 Q2 CLINICAL NEUROLOGY

Sleep Medicine Clinics Pub Date : 2024-05-28 DOI:10.1016/j.jsmc.2024.04.001

Budhima Nanayakkara MBBS, PhB , Stephen McNamara BSc(Med), MBBS, PhD

引用次数: 0

摘要

慢性高碳酸血症呼吸衰竭发生在多种与通气不足相关的疾病中。慢性高碳酸血症的发病机制包括增加二氧化碳代谢生成、降低分钟通气量（V'e）或增加死腔分数（Vd/Vt）等一系列过程。病理生理学的基本原理是负荷增加与呼吸泵补偿能力下降之间的不匹配。尽管在部分中枢性通气不足疾病中，神经呼吸驱动力可能会下降，但在试图维持负荷-容量平衡时，神经呼吸驱动力通常会增加。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pathophysiology of Chronic Hypercapnic Respiratory Failure

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来源期刊

Sleep Medicine Clinics CLINICAL NEUROLOGY-

CiteScore

6.00

自引率

3.60%

发文量

期刊介绍： Sleep Medicine Clinics provides a forum for invited, topical reviews in this rapidly growing field. Each issue, guest edited by a leader in the field of Sleep Medicine, provides expert, state-of-the-art reviews on a single topic, making ample use of figures, diagrams, and tables. Topics such as Obstructive Sleep Apnea, Insomnia, and Parasomnias are presented clearly and comprehensively in the Sleep Medicine Clinics?perfect for any clinician who works with patients suffering from sleep disorders.