[肝胆和移植手术中的性别差异]。

Chirurgie (Heidelberg, Germany) Pub Date : 2024-09-01 Epub Date: 2024-08-01 DOI:10.1007/s00104-024-02139-1
H Linge, N Nevermann, M Schmelzle, M Quante
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引用次数: 0

摘要

肝胆和移植手术中的性别差异对诊断、治疗和长期疗效起着决定性作用。男性在肝癌切除术后出现晚期复发和癌症特异性死亡的风险更高。强调筛查建议和确保平等获得治疗方案对于最大限度地减少差异至关重要。在肾脏和肝脏移植手术中,女性被列入移植名单的频率较低,等待时间较长,而男性则在等待名单中占主导地位。由于药物相容性方面的性别差异,有必要采用不同的剂量。要确保移植治疗的公平性,还需要进一步的研究。考虑到这些差异的个性化治疗可以提高治疗效果和患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Sex differences in hepatobiliary and transplantation surgery].

Gender-specific differences in hepatobiliary and transplantation surgery are decisive for the diagnosis, treatment and long-term outcomes. Men exhibit a higher risk of late recurrences and cancer-specific death after liver cancer resection. The emphasis on screening recommendations and ensuring equal access to treatment options are vital to minimize disparities. In kidney and liver transplantations, women are less frequently listed and endure longer waiting times, while men dominate the waiting list. Gender-specific disparities in drug compatibility necessitate differentiated dosing. Further studies are needed to ensure equity in transplantation treatment. Individualized treatment considering these differences can enhance treatment outcomes and the quality of life of patients.

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