[患有散发性伯基特淋巴瘤的青少年中出现异常表现的孤立性脾肿瘤]。

IF 0.5 Q4 PEDIATRICS
Carlos Julian Diaz-Torres, Ricardo Abanto Hinostroza
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引用次数: 0

摘要

伯基特淋巴瘤是一种非霍奇金B细胞淋巴瘤,在儿童中发病率很高。散发性伯基特淋巴瘤的腹部表现众所周知,从非特异性症状到肠套叠引起的肠梗阻,不一而足;然而,肿块样脾脏受累却鲜有报道:临床病例:一名 13 岁女性患者因腹痛、进行性体重减轻和发热就诊。影像学检查显示有脾脏肿块、肠道增厚和回肠肠套叠。脾脏活检组织病理分析显示为伯基特淋巴瘤。第一周期化疗(BFM95-NHL方案)后,腹部症状缓解,没有发现其他肠套叠的迹象,脾脏肿块也明显缩小:结论:小儿伯基特淋巴瘤可表现为界限清楚的脾脏肿瘤,不会引起脾脏肿大。结论:小儿伯基特淋巴瘤可表现为界限清楚的脾脏肿瘤,不会引起脾脏肿大,而且无需手术治疗,因为化疗即可治愈。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Solitary splenic neoplasm as an unusual presentation in an adolescent with sporadic Burkitt lymphoma].

Burkitt lymphoma is a non-Hodgkin B-cell lymphoma with a high prevalence in the pediatric population. Abdominal manifestations are well known in sporadic Burkitt lymphoma and vary from nonspecific symptoms to intestinal obstruction due to intussusception; however, mass-like splenic involvement has been scarcely described.

Objective: To present a case of a patient with a splenic mass whose histopathological analysis revealed Burkitt lymphoma.

Clinical case: A 13-year-old female patient presented with abdominal pain, progressive weight loss, and fever. Imaging studies showed a splenic mass, intestinal thickening, and ileal intussusception. Histopathological analysis of spleen biopsy revealed Burkitt lymphoma. After the first cycle of chemotherapy (BFM95-NHL protocol), abdominal symptoms resolved; no other signs suggestive of intussusception were observed, as well as a significant reduction of the splenic mass was observed.

Conclusions: Burkitt lymphoma in pediatric patients can present as a well-defined splenic tumor, causing no splenomegaly. In addition, its management does not require surgery since it can be resolved with chemotherapy.

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