IBEX 知识库：与开放科学携手实现更多目标

arXiv - QuanBio - Tissues and Organs Pub Date : 2024-07-26 DOI:arxiv-2407.19059

Andrea J. RadtkeLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Ifeanyichukwu AnidiCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Leanne ArakkalLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Armando Arroyo-MejiasLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Rebecca T. BeuschelLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Katy BornerDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA, Colin J. ChuUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Beatrice ClarkLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Menna R. ClatworthyCambridge Institute for Therapeutic Immunology and Infectious Diseases, University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, UK, Jake ColauttiMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Joshua CroteauDepartment of Business Development, BioLegend Inc., San Diego, CA, USA, Saven DenhaMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Rose DeverFunctional Immunogenomics Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA, Walderez O. DutraLaboratory of Cell-Cell Interactions, Department of Morphology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, Sonja FritzscheMax-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Spencer FullamDivision of Rheumatology, Rush University Medical Center, Chicago, IL, USA, Michael Y. GernerDepartment of Immunology, University of Washington School of Medicine, Seattle, WA, USA, Anita GolaRobin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA, Kenneth J. GollobCenter for Research in Immuno-oncology, Jonathan M. HernandezSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Jyh Liang HorLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Hiroshi IchiseLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Zhixin JingLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Danny JonigkInstitute of Pathology, Aachen Medical University, RWTH Aachen, Aachen, Germany, Evelyn KandovLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Wolfgang KastenmuellerWurzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany, Joshua F. E. KoenigMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Aanandita KothurkarUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Alexandra Y. KreinsInfection Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK, Ian LambornLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Yuri LinSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Katia Luciano Pereira MoraisCenter for Research in Immuno-oncology, Aleksandra LunichCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Jean C. S. LuzViral Vector Laboratory, Cancer Institute of Sao Paulo, University of Sao Paulo, SP, Brazil, Ryan B. MacDonaldUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Chen MakranzNeuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Vivien I. MaltezDivision of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA, Ryan V. MoriatyDepartment of Cellular and Developmental Biology, Northwestern University, Chicago, IL, USA, Juan M. Ocampo-GodinezLaboratorio de Bioingenieria de Tejidos, Departamento de Estudios de Posgrado e Investigacion, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, Vitoria M. OlynthoMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Kartika PadhanLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Kirsten RemmertSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Nathan RichozCambridge Institute for Therapeutic Immunology and Infectious Diseases, University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, UK, Edward C. SchromLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Wanjing ShangLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Lihong ShiLaboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Rochelle M. ShihLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Emily SperanzaFlorida Research and Innovation Center, Cleveland Clinic Lerner Research Institute, Port Saint Lucie, FL, USA, Salome StierliInstitute of Anatomy, University of Zurich, Zurich, Switzerland, Sarah A. TeichmannCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, UK, Tibor Z. VeresLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Megan VierhoutMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Brianna T. WachterLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Adam K. Wade-VallanceLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Margaret WilliamsCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Nathan ZanggerInstitute of Microbiology, ETH Zurich, Zurich, Switzerland, Ronald N. GermainLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA and Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Ziv YanivBioinformatics and Computational Bioscience Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA

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BeuschelLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Katy BornerDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA, Colin J. ChuUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Beatrice ClarkLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Menna R. ClatworthyCambridge Institute for Therapeutic Immunology and Infectious Diseases, University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, UK, Jake ColauttiMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Joshua CroteauDepartment of Business Development, BioLegend Inc., San Diego, CA, USA, Saven DenhaMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Rose DeverFunctional Immunogenomics Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA, Walderez O. DutraLaboratory of Cell-Cell Interactions, Department of Morphology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, Sonja FritzscheMax-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Spencer FullamDivision of Rheumatology, Rush University Medical Center, Chicago, IL, USA, Michael Y. GernerDepartment of Immunology, University of Washington School of Medicine, Seattle, WA, USA, Anita GolaRobin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA, Kenneth J. GollobCenter for Research in Immuno-oncology, Jonathan M. HernandezSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Jyh Liang HorLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Hiroshi IchiseLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Zhixin JingLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Danny JonigkInstitute of Pathology, Aachen Medical University, RWTH Aachen, Aachen, Germany, Evelyn KandovLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Wolfgang KastenmuellerWurzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany, Joshua F. E. KoenigMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Aanandita KothurkarUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Alexandra Y. KreinsInfection Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK, Ian LambornLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Yuri LinSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Katia Luciano Pereira MoraisCenter for Research in Immuno-oncology, Aleksandra LunichCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Jean C. S. LuzViral Vector Laboratory, Cancer Institute of Sao Paulo, University of Sao Paulo, SP, Brazil, Ryan B. MacDonaldUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Chen MakranzNeuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Vivien I. MaltezDivision of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA, Ryan V. MoriatyDepartment of Cellular and Developmental Biology, Northwestern University, Chicago, IL, USA, Juan M. Ocampo-GodinezLaboratorio de Bioingenieria de Tejidos, Departamento de Estudios de Posgrado e Investigacion, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, Vitoria M. OlynthoMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Kartika PadhanLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Kirsten RemmertSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Nathan RichozCambridge Institute for Therapeutic Immunology and Infectious Diseases, University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, UK, Edward C. SchromLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Wanjing ShangLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Lihong ShiLaboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Rochelle M. ShihLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Emily SperanzaFlorida Research and Innovation Center, Cleveland Clinic Lerner Research Institute, Port Saint Lucie, FL, USA, Salome StierliInstitute of Anatomy, University of Zurich, Zurich, Switzerland, Sarah A. TeichmannCambridge Stem Cell Institute, Jeffrey Cheah Biomedical Centre, Puddicombe Way, Cambridge Biomedical Campus, Cambridge, UK, Tibor Z. VeresLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Megan VierhoutMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Brianna T. WachterLaboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Adam K. Wade-VallanceLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Margaret WilliamsCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Nathan ZanggerInstitute of Microbiology, ETH Zurich, Zurich, Switzerland, Ronald N. GermainLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA and Lymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Ziv YanivBioinformatics and Computational Bioscience Branch, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA","doi":"arxiv-2407.19059","DOIUrl":null,"url":null,"abstract":"Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for\nhighly multiplexed imaging of diverse tissues. 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RadtkeLymphocyte Biology Section and Center for Advanced Tissue Imaging, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Ifeanyichukwu AnidiCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Leanne ArakkalLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Armando Arroyo-MejiasLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Rebecca T. BeuschelLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Katy BornerDepartment of Intelligent Systems Engineering, Indiana University, Bloomington, IN, USA, Colin J. ChuUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Beatrice ClarkLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Menna R. ClatworthyCambridge Institute for Therapeutic Immunology and Infectious Diseases, University of Cambridge Department of Medicine, Molecular Immunity Unit, Laboratory of Molecular Biology, Cambridge, UK, Jake ColauttiMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Joshua CroteauDepartment of Business Development, BioLegend Inc., San Diego, CA, USA, Saven DenhaMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Rose DeverFunctional Immunogenomics Unit, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD, USA, Walderez O. DutraLaboratory of Cell-Cell Interactions, Department of Morphology, Institute of Biological Sciences, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil, Sonja FritzscheMax-Delbrueck-Center for Molecular Medicine in the Helmholtz Association, Spencer FullamDivision of Rheumatology, Rush University Medical Center, Chicago, IL, USA, Michael Y. GernerDepartment of Immunology, University of Washington School of Medicine, Seattle, WA, USA, Anita GolaRobin Chemers Neustein Laboratory of Mammalian Cell Biology and Development, The Rockefeller University, New York, NY, USA, Kenneth J. GollobCenter for Research in Immuno-oncology, Jonathan M. HernandezSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Jyh Liang HorLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Hiroshi IchiseLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Zhixin JingLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Danny JonigkInstitute of Pathology, Aachen Medical University, RWTH Aachen, Aachen, Germany, Evelyn KandovLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Wolfgang KastenmuellerWurzburg Institute of Systems Immunology, Max Planck Research Group at the Julius-Maximilians-Universitat Wurzburg, Wurzburg, Germany, Joshua F. E. KoenigMcMaster Immunology Research Centre, Schroeder Allergy and Immunology Research Institute, Department of Medicine, Faculty of Health Sciences, McMaster University, Hamilton, ON, Canada, Aanandita KothurkarUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Alexandra Y. KreinsInfection Immunity and Inflammation Research and Teaching Department, University College London Great Ormond Street Institute of Child Health, London, UK, Ian LambornLymphocyte Biology Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA, Yuri LinSurgical Oncology Program, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Katia Luciano Pereira MoraisCenter for Research in Immuno-oncology, Aleksandra LunichCritical Care Medicine and Pulmonary Branch, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA, Jean C. S. LuzViral Vector Laboratory, Cancer Institute of Sao Paulo, University of Sao Paulo, SP, Brazil, Ryan B. MacDonaldUCL Institute of Ophthalmology and NIHR Moorfields Biomedical Research Centre, London, UK, Chen MakranzNeuro-Oncology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA, Vivien I. MaltezDivision of Allergy, Immunology and Rheumatology, Department of Pediatrics, University of California San Diego, La Jolla, CA, USA, Ryan V. MoriatyDepartment of Cellular and Developmental Biology, Northwestern University, Chicago, IL, USA, Juan M. Ocampo-GodinezLaboratorio de Bioingenieria de Tejidos, Departamento de Estudios de Posgrado e Investigacion, Universidad Nacional Autonoma de Mexico, Mexico City, Mexico, Vitoria M. 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摘要

Iterative Bleaching Extends multipleXity (IBEX) 是一种对不同组织进行高度多重成像的多功能方法。基于开放科学原则，我们创建了 IBEX 知识库，这是一个提供试剂、规程和更多信息的资源库，以增强创新能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The IBEX Knowledge-Base: Achieving more together with open science

Iterative Bleaching Extends multipleXity (IBEX) is a versatile method for highly multiplexed imaging of diverse tissues. Based on open science principles, we created the IBEX Knowledge-Base, a resource for reagents, protocols and more, to empower innovation.

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arXiv - QuanBio - Tissues and Organs

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