{"title":"金属纳米颗粒及其对微生物的毒性影响","authors":"Arulanandar Abishagu, Pandian Kannan, Uthandi Sivakumar, Narayanan Manikanda Boopathi, Murugaiyan Senthilkumar","doi":"10.1007/s11756-024-01760-z","DOIUrl":null,"url":null,"abstract":"<p>Metal nanoparticles (MNPs) have gained considerable attention for their diverse applications across various fields, including medicine, electronics, and environmental remediation, agriculture and manufacturing. The relationship between metal nanoparticles and the microorganisms, highlighting the diverse mechanisms through which nanotoxicity manifests and influences microbial communities. Metal nanoparticles, owing to their unique physicochemical properties, can interact with the microbiome directly or indirectly, disrupting microbial homeostasis and functionality. The interactions are complex, involving mechanisms such as membrane disorganization, reactive oxygen species (ROS) generation, and oxidative Deoxyribonucleic acid (DNA) damage. Comprehending the different types of metal nanoparticles, their antimicrobial properties, and the mechanisms that underlie their nanotoxicity towards microorganisms is imperative for the secure advancement and implementation of nanotechnology, paving the way for innovative strategies to mitigate adverse effects and promote sustainable nanomaterial applications. Nanotechnology has witnessed remarkable advancements in various fields, yet concerns regarding its potential adverse effects on biological systems, particularly the microbiome, have emerged as a significant area of investigation. This abstract highlight the importance of interdisciplinary approaches encompassing nanoscience, microbiology, and toxicology to unravel the intricate dynamics of metal nanoparticle-microbes’ interactions and facilitate the design of safer nanoproducts for diverse applications. Overall, this study emphasizes the need for more investigation to clarify the complex dynamics of metal nanoparticles in microbial environments and their long-term effects on sustainability and environmental health.</p>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Metal nanoparticles and their toxicity impacts on microorganisms\",\"authors\":\"Arulanandar Abishagu, Pandian Kannan, Uthandi Sivakumar, Narayanan Manikanda Boopathi, Murugaiyan Senthilkumar\",\"doi\":\"10.1007/s11756-024-01760-z\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Metal nanoparticles (MNPs) have gained considerable attention for their diverse applications across various fields, including medicine, electronics, and environmental remediation, agriculture and manufacturing. The relationship between metal nanoparticles and the microorganisms, highlighting the diverse mechanisms through which nanotoxicity manifests and influences microbial communities. Metal nanoparticles, owing to their unique physicochemical properties, can interact with the microbiome directly or indirectly, disrupting microbial homeostasis and functionality. The interactions are complex, involving mechanisms such as membrane disorganization, reactive oxygen species (ROS) generation, and oxidative Deoxyribonucleic acid (DNA) damage. Comprehending the different types of metal nanoparticles, their antimicrobial properties, and the mechanisms that underlie their nanotoxicity towards microorganisms is imperative for the secure advancement and implementation of nanotechnology, paving the way for innovative strategies to mitigate adverse effects and promote sustainable nanomaterial applications. Nanotechnology has witnessed remarkable advancements in various fields, yet concerns regarding its potential adverse effects on biological systems, particularly the microbiome, have emerged as a significant area of investigation. This abstract highlight the importance of interdisciplinary approaches encompassing nanoscience, microbiology, and toxicology to unravel the intricate dynamics of metal nanoparticle-microbes’ interactions and facilitate the design of safer nanoproducts for diverse applications. Overall, this study emphasizes the need for more investigation to clarify the complex dynamics of metal nanoparticles in microbial environments and their long-term effects on sustainability and environmental health.</p>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2024-07-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"99\",\"ListUrlMain\":\"https://doi.org/10.1007/s11756-024-01760-z\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1007/s11756-024-01760-z","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Metal nanoparticles and their toxicity impacts on microorganisms
Metal nanoparticles (MNPs) have gained considerable attention for their diverse applications across various fields, including medicine, electronics, and environmental remediation, agriculture and manufacturing. The relationship between metal nanoparticles and the microorganisms, highlighting the diverse mechanisms through which nanotoxicity manifests and influences microbial communities. Metal nanoparticles, owing to their unique physicochemical properties, can interact with the microbiome directly or indirectly, disrupting microbial homeostasis and functionality. The interactions are complex, involving mechanisms such as membrane disorganization, reactive oxygen species (ROS) generation, and oxidative Deoxyribonucleic acid (DNA) damage. Comprehending the different types of metal nanoparticles, their antimicrobial properties, and the mechanisms that underlie their nanotoxicity towards microorganisms is imperative for the secure advancement and implementation of nanotechnology, paving the way for innovative strategies to mitigate adverse effects and promote sustainable nanomaterial applications. Nanotechnology has witnessed remarkable advancements in various fields, yet concerns regarding its potential adverse effects on biological systems, particularly the microbiome, have emerged as a significant area of investigation. This abstract highlight the importance of interdisciplinary approaches encompassing nanoscience, microbiology, and toxicology to unravel the intricate dynamics of metal nanoparticle-microbes’ interactions and facilitate the design of safer nanoproducts for diverse applications. Overall, this study emphasizes the need for more investigation to clarify the complex dynamics of metal nanoparticles in microbial environments and their long-term effects on sustainability and environmental health.
期刊介绍:
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.