José M Pérez de la Lastra, Samuel J T Wardell, Tarun Pal, Cesar de la Fuente-Nunez, Daniel Pletzer
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引用次数: 0
摘要
耐药性细菌的出现对现代医学构成了重大挑战。为此,人工智能(AI)和机器学习(ML)算法已成为对抗抗菌药耐药性(AMR)的有力工具。本综述旨在探讨人工智能/ML 在 AMR 管理中的作用,重点是识别病原体、了解耐药性模式、预测治疗结果和发现新的抗生素制剂。人工智能/ML 的最新进展使人们能够高效地分析大型数据集,从而在最少人工干预的情况下可靠地预测 AMR 的趋势和治疗反应。ML 算法可以分析基因组数据,找出与抗生素耐药性相关的遗传标记,从而制定有针对性的治疗策略。此外,人工智能/ML 技术在优化用药和开发传统抗生素替代品方面也大有可为。通过分析患者数据和临床结果,这些技术可以帮助医疗服务提供者诊断感染、评估感染严重程度并选择适当的抗菌疗法。虽然人工智能/移动医疗在临床环境中的整合仍处于起步阶段,但数据质量和算法开发方面的进步表明,广泛的临床应用即将到来。总之,AI/ML 在改善 AMR 管理和治疗效果方面大有可为。
From Data to Decisions: Leveraging Artificial Intelligence and Machine Learning in Combating Antimicrobial Resistance - a Comprehensive Review.
The emergence of drug-resistant bacteria poses a significant challenge to modern medicine. In response, Artificial Intelligence (AI) and Machine Learning (ML) algorithms have emerged as powerful tools for combating antimicrobial resistance (AMR). This review aims to explore the role of AI/ML in AMR management, with a focus on identifying pathogens, understanding resistance patterns, predicting treatment outcomes, and discovering new antibiotic agents. Recent advancements in AI/ML have enabled the efficient analysis of large datasets, facilitating the reliable prediction of AMR trends and treatment responses with minimal human intervention. ML algorithms can analyze genomic data to identify genetic markers associated with antibiotic resistance, enabling the development of targeted treatment strategies. Additionally, AI/ML techniques show promise in optimizing drug administration and developing alternatives to traditional antibiotics. By analyzing patient data and clinical outcomes, these technologies can assist healthcare providers in diagnosing infections, evaluating their severity, and selecting appropriate antimicrobial therapies. While integration of AI/ML in clinical settings is still in its infancy, advancements in data quality and algorithm development suggest that widespread clinical adoption is forthcoming. In conclusion, AI/ML holds significant promise for improving AMR management and treatment outcome.
期刊介绍:
Journal of Medical Systems provides a forum for the presentation and discussion of the increasingly extensive applications of new systems techniques and methods in hospital clinic and physician''s office administration; pathology radiology and pharmaceutical delivery systems; medical records storage and retrieval; and ancillary patient-support systems. The journal publishes informative articles essays and studies across the entire scale of medical systems from large hospital programs to novel small-scale medical services. Education is an integral part of this amalgamation of sciences and selected articles are published in this area. Since existing medical systems are constantly being modified to fit particular circumstances and to solve specific problems the journal includes a special section devoted to status reports on current installations.