格陵兰 ACCEPT 队列中的金属暴露:跟踪调查以及与其他北极地区人群的比较。

IF 1.3 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Maria Wielsøe, Manhai Long, Jens Søndergaard, Eva Cecilie Bonefeld-Jørgensen
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引用次数: 0

摘要

人类通过饮食和生活方式(如吸烟)接触金属。一些金属是人体生理功能所必需的,而另一些则是非必需的,可能对人体有毒。这项研究跟踪格陵兰 ACCEPT 出生队列(母亲和父亲)中的金属浓度,并与其他北极人群进行比较。2019 年至 2020 年的数据包括居住在努克、西西米尤特和伊卢利萨特的 101 名母亲和 76 名父亲(24-55 岁)的血液金属浓度、生活方式和食物频率问卷。超过汞国际指导值的比例很高(25-45%)。从怀孕到出生后 3-5 年的随访期间,母亲体内的金属浓度发生了显著变化;有些浓度上升,有些浓度下降。大多数金属在母亲和父亲之间存在明显差异,少数金属在不同居住城镇之间也存在差异。有几种金属与海洋食物摄入量和社会经济因素有明显的相关性,但相关性的方向各不相同。传统海洋食物摄入量与硒、砷和汞呈正相关。据我们所知,这项研究提供了格陵兰岛男性和女性接触金属的最新数据,阐明了北极地区人口接触金属的来源,并证明有必要继续进行生物监测,以跟踪汞指导值的超标情况。[图:见正文]。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Metal exposure in the Greenlandic ACCEPT cohort: follow-up and comparison with other Arctic populations.

Humans are exposed to metals through diet and lifestyle e.g. smoking. Some metals are essential for physiologically body functions, while others are non-essential and can be toxic to humans. This study follows up on metal concentrations in the Greenlandic ACCEPT birth-cohort (mothers and fathers) and compares with other Arctic populations. The data from 2019 to 2020 include blood metal concentrations, lifestyle and food frequency questionnaires from 101 mothers and 76 fathers, 24-55 years, living in Nuuk, Sisimiut, and Ilulissat. A high percentage (25-45%) exceeded international guidance values for Hg. For the mothers, the metal concentrations changed significantly from inclusion at pregnancy to this follow-up 3-5 years after birth; some increased and others decreased. Most metals differed significantly between mothers and fathers, while few also differed between residential towns. Several metals correlated significantly with marine food intake and socio-economic factors, but the direction of the correlations varied. Traditional marine food intake was associated positively with Se, As and Hg. To the best of our knowledge, this study provides the most recent data on metal exposure of both men and women in Greenland, elucidating metal exposure sources among Arctic populations, and documents the need for continuing biomonitoring to follow the exceeding of guidance values for Hg. [Figure: see text].

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来源期刊
International Journal of Circumpolar Health
International Journal of Circumpolar Health 医学-公共卫生、环境卫生与职业卫生
CiteScore
2.10
自引率
15.40%
发文量
51
审稿时长
6-12 weeks
期刊介绍: The International Journal of Circumpolar Health is published by Taylor & Francis on behalf of the Circumpolar Health Research Network [CircHNet]. The journal follows the tradition initiated by its predecessor, Arctic Medical Research. The journal specializes in circumpolar health. It provides a forum for many disciplines, including the biomedical sciences, social sciences, and humanities as they relate to human health in high latitude environments. The journal has a particular interest in the health of indigenous peoples. It is a vehicle for dissemination and exchange of knowledge among researchers, policy makers, practitioners, and those they serve. International Journal of Circumpolar Health welcomes Original Research Articles, Review Articles, Short Communications, Book Reviews, Dissertation Summaries, History and Biography, Clinical Case Reports, Public Health Practice, Conference and Workshop Reports, and Letters to the Editor.
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