类癌性心脏病

Nicole Ross, MSN, CRNP, AOCNP
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引用次数: 0

摘要

类癌性心脏病(CHD)是一种罕见但可能危及生命的晚期神经内分泌肿瘤类癌综合征后遗症。这些肿瘤可分泌血管活性物质,其中最常见的是血清素。类癌性心脏病通常累及右侧心脏瓣膜,最终导致右心衰竭。在诊断和治疗期间监测 N 端前 B 型利钠肽和 5-羟基吲哚乙酸以及心脏超声心动图有助于筛查类癌性心脏病。许多患者没有得到适当的筛查。对患有冠心病的患者进行多学科治疗是理想的选择,其中包括肿瘤内科、心脏内科和心胸外科。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carcinoid Heart Disease
Carcinoid heart disease (CHD) is a rare but potentially life-threatening sequela of advanced neuroendocrine neoplasm with carcinoid syndrome. These tumors can secrete vasoactive substances of which serotonin is the most prevalent. Carcinoid heart disease typically involves the right-sided heart valves and eventually leads to right heart failure. Monitoring N-terminal pro–B-type natriuretic peptide and 5-hydroxyindoleacetic acid at diagnosis and during treatment, as well as cardiac echocardiogram, helps to screen for CHD. Many patients are not screened for this appropriately. Multidisciplinary care for patients with CHD is ideal and involves medical oncology, cardiology, and cardiothoracic surgery.
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