苦瓜（Momordica charantia）对成人人体测量指数的影响：随机对照试验的系统回顾和荟萃分析

IF 2.5 3区生物学 Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY

Prostaglandins & other lipid mediators Pub Date : 2024-07-28 DOI:10.1016/j.prostaglandins.2024.106877

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引用次数: 0

摘要

关于苦瓜（Momordica charantia）补充剂对人体测量指数的影响，目前还存在争议。因此，我们旨在通过系统回顾和试验荟萃分析来澄清苦瓜的这一作用。截至 2023 年 8 月，PubMed、Web of Sciences、Scopus、Embase 和 Cochrane Library 等网络数据库收录了所有关于苦瓜对人体测量指数影响的临床试验。荟萃分析共纳入了 10 项研究，共 448 人。对有 448 人参加的 10 项试验进行的荟萃分析表明，体重（BW）（WMD：0.04 公斤；95 %CI：-0.16-0.25；P =0.651）、体重指数（BMI）（WMD：-0.18 公斤/平方米；95 %CI：-0.43-0.P =0.171）、腰围（WC）（WMD：-0.95 厘米；95 % CI：-3.05-1.16；P =0.372）和体脂百分比（PBF）（WMD：-0.99；95 % CI：-2.33-0.35；P =0.141）。补充苦瓜对体重、体重指数、腹围和体脂率没有明显影响。有必要进行更多大规模和高质量的 RCT 研究来证实这些结果。

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The effects of bitter melon (Momordica charantia) on anthropometric indices in adults: A systematic review and meta-analysis of randomized controlled trials

There is controversial data on the impacts of bitter melon (Momordica charantia) supplementations on anthropometric indices. Thus, we aimed to clarify this role of bitter melon through a systematic review, and meta-analysis of the trials. All clinical trials conducted on the impact of bitter melon on anthropometric indices were published until August 2023 in PubMed, Web of Sciences, Scopus, Embase, and Cochrane Library web databases included. Overall, 10 studies with 448 individuals were included in the meta-analysis. Meta-analysis of 10 trials with 448 participants revealed no significant reductions in body weight (BW) (WMD: 0.04 Kg; 95 %CI: −0.16–0.25; P =0.651), body mass index (BMI) (WMD: −0.18 kg/m2; 95 %CI: −0.43–0.07; P =0.171), waist circumference (WC) (WMD: −0.95 cm; 95 % CI: −3.05–1.16; p =0.372), and percentage of body fat (PBF) (WMD: −0.99; 95 % CI: −2.33–0.35; p =0.141) following bitter melon supplementation. There was no significant impact of bitter melon supplementation on BW, BMI, WC, and PBF. More large-scale and high-quality RCTs are necessary to confirm these results.

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来源期刊

Prostaglandins & other lipid mediators 生物-生化与分子生物学

CiteScore

5.80

自引率

3.40%

发文量

审稿时长

2 months

期刊介绍： Prostaglandins & Other Lipid Mediators is the original and foremost journal dealing with prostaglandins and related lipid mediator substances. It includes basic and clinical studies related to the pharmacology, physiology, pathology and biochemistry of lipid mediators. Prostaglandins & Other Lipid Mediators invites reports of original research, mini-reviews, reviews, and methods articles in the basic and clinical aspects of all areas of lipid mediator research: cell biology, developmental biology, genetics, molecular biology, chemistry, biochemistry, physiology, pharmacology, endocrinology, biology, the medical sciences, and epidemiology. Prostaglandins & Other Lipid Mediators also accepts proposals for special issue topics. The Editors will make every effort to advise authors of the decision on the submitted manuscript within 3-4 weeks of receipt.