46.径流模式对比剂(RPC)对使用可转向导管进行硬膜外粘连溶解术的长期疗效的影响:一项单中心观察性研究

Q3 Medicine
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引用次数: 0

摘要

背景 CONTEXTE使用可转向导管的硬膜外粘连溶解疗法自 2018 年 4 月起在日本被纳入保险范围,但缺乏对其治疗效果进行放射学评估的报告,从而导致了不确定性。目的在这项研究中,我们调查了术中成像(放射线造影)中的径流模式对比(RPC)描绘如何影响治疗结果,并报告了我们的发现。患者样本2018年8月至2021年12月期间,因主诉下背痛和腿痛而接受硬膜外粘连溶解术的患者共188例,其中男性89例,女性99例,平均年龄72.9岁。目标病症包括腰椎管狭窄症、椎间盘突出症、腰椎滑脱症、非特异性下背痛、骶骨囊肿、腰部手术失败综合征和多次手术后背。结果测量基于视觉模拟量表(VAS)的改善率。方法评估标准包括术后早期(1 周)症状改善,6 个月和 1 年时 VAS 改善率达到或超过 50%,即为有效,并与术中对比放射成像中是否出现 RPC 进行比较。结果术后早期,122 例(65%)报告主观症状改善(P <0.05),其中 67 例(55%)出现 RPC。6 个月后,78 例(42%)显示有效,包括 53 例(69%)的 RPC。1 年后,58 例(31%)显示有效,其中 47 例(82%)为 RPC。此外,在 41 例(21.8%)需要手术的病例中,不存在 RPC。我们的研究结果表明,RPC 对长期预后有潜在影响,这表明有可能根据术中对比成像结果预测治疗效果。FDA 设备/药物状态本摘要未讨论或包含任何适用的设备或药物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
46. Effect of runoff pattern contrast (RPC) on the long-term outcomes of epidural adhesiolysis using steerable catheters: a single-center observational study

BACKGROUND CONTEXT

Epidural adhesiolytic therapy using a steerable catheter has been covered by insurance in Japan since April 2018, but there is a lack of reports radiologically evaluating its therapeutic effects, leading to uncertainty.

PURPOSE

In this study, we investigated how the depiction of runoff pattern contrast (RPC) in intraoperative imaging (radiculography) affects treatment outcomes and report our findings.

STUDY DESIGN/SETTING

A single-center observational study.

PATIENT SAMPLE

A total of 188 cases, consisting of 89 males and 99 females with a mean age of 72.9 years, who underwent epidural adhesiolysis for complaints of lower back pain and leg pain from August 2018 to December 2021. Targeted conditions included lumbar spinal stenosis, intervertebral disc herniation, lumbar spondylolisthesis, nonspecific lower back pain, sacral cyst, failed back surgery syndrome, and multiple operation back.

OUTCOME MEASURES

Improvement rate based on the Visual Analog Scale (VAS).

METHODS

Evaluation criteria included the presence of early postoperative (1 week) symptom improvement, VAS improvement rates of 50% or more at 6 months and 1 year as effective, and comparison with the presence of RPC in intraoperative contrast radiography.

RESULTS

Early postoperatively, 122 cases (65%) reported subjective symptom improvement (P < 0.05), with RPC in 67 cases (55%). At 6 months, 78 cases (42%) showed effectiveness, including RPC in 53 cases (69%). After 1 year, 58 cases (31%) demonstrated effectiveness, with RPC in 47 cases (82%). Additionally, among the 41 cases (21.8%) that required surgery, RPC was absent.

CONCLUSIONS

The effectiveness of epidural adhesiolysis is not persistent and is often limited to a specific period. Our results suggest the potential impact of RPC on long-term outcomes, indicating the possibility of predicting treatment effectiveness based on intraoperative contrast imaging findings.

FDA Device/Drug Status

This abstract does not discuss or include any applicable devices or drugs.

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CiteScore
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