分析子宫切除术和输卵管切除术的 10 年时间趋势:关注子宫内膜取样和子宫内膜癌的风险因素

IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
A. Yurtkal, Mujde Canday
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Risk factors were evaluated in confirmed cases of endometrial cancer and atypic endometrial hyperplasia based on pathology results. The analyses were performed using IBM SPSS 20 statistical analysis software. Results In our study,752 patients(mean age: 52±8.2) underwent various hysterectomy procedures, with total abdominal hysterectomy being the most frequent(73.3%). The primary indication was uterine leiomyomas-adenomyomas(33.5%). Endometrial sampling was performed in 57.2% of patients, showing no significant difference in reliability(p=0.143) and endometrial cancer diagnosis(p=0.334). Among 38 patients diagnosed with endometrial cancer, approximately 28.9%(11 patients) did not undergo preoperative endometrial sampling. Further examination revealed that these patients were obese, 63.6% presented with spotting-like bleeding, and most were in the postmenopausal period. 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引用次数: 0

摘要

背景 子宫切除术是治疗各种良性和恶性妇科疾病的常用方法。我们的研究旨在利用多年来积累的数据对子宫切除术进行全面透视,并为临床医生提供对子宫切除手术的准确见解。所有患者的全面病史均作为主要数据进行了详细审查。手术过程按年份进行分类和比较。此外,还研究了手术适应症、术前子宫内膜取样以及最终子宫切除术标本的病理结果。根据病理结果对确诊的子宫内膜癌和非典型子宫内膜增生病例的风险因素进行了评估。分析使用 IBM SPSS 20 统计分析软件进行。结果 在我们的研究中,752 名患者(平均年龄:52±8.2)接受了各种子宫切除术,其中全腹子宫切除术最多见(73.3%)。子宫切除术的主要适应症是子宫肌瘤-腺肌瘤(33.5%)。57.2%的患者进行了子宫内膜取样,在可靠性(P=0.143)和子宫内膜癌诊断(P=0.334)方面无显著差异。在 38 名确诊为子宫内膜癌的患者中,约有 28.9%(11 名患者)未进行术前子宫内膜取样。进一步检查发现,这些患者均为肥胖者,63.6%的患者有点滴样出血,且大多数处于绝经后时期。这些患者和非典型增生患者的危险因素显示,阳性家族史(P=0.037)和雌激素治疗史(P=0.028)具有统计学意义。在 536 例输卵管切除术中,有 236 例是为 50 岁以下的女性实施的。广泛采用非子宫切除术是降低手术率的关键。医生必须整合当前的文献,完善微创方法的技能,并提高手术技术,以实现治疗恶性前病变和子宫内膜癌的理想方法。提供临床数据以个性化算法和治疗方法将加强文献、提高该领域的水平并增加知识的适用性,从而个性化地实施理想的算法和治疗方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analyzing 10-year time trends for Hysterectomy and Oophorectomy: Focus on Endometrial sampling and risk factors for Endometrial Cancer
Background Hysterectomy is a versatile and commonly employed treatment option for various benign and malignant gynecological conditions. Our study aims to take a comprehensive perspective on hysterectomy over the years using accumulated data and provide clinicians with an accurate insight into the hysterectomy operation.Material-Method This retrospective observational study was conducted on women who underwent hysterectomy at our clinic between 2012 and 2021. Comprehensive medical histories of all patients were thoroughly reviewed as the primary data. Surgical procedures were categorized and compared by year. Operation indications, preoperative endometrial sampling, and the pathology results of the final hysterectomy specimens were also examined. Risk factors were evaluated in confirmed cases of endometrial cancer and atypic endometrial hyperplasia based on pathology results. The analyses were performed using IBM SPSS 20 statistical analysis software. Results In our study,752 patients(mean age: 52±8.2) underwent various hysterectomy procedures, with total abdominal hysterectomy being the most frequent(73.3%). The primary indication was uterine leiomyomas-adenomyomas(33.5%). Endometrial sampling was performed in 57.2% of patients, showing no significant difference in reliability(p=0.143) and endometrial cancer diagnosis(p=0.334). Among 38 patients diagnosed with endometrial cancer, approximately 28.9%(11 patients) did not undergo preoperative endometrial sampling. Further examination revealed that these patients were obese, 63.6% presented with spotting-like bleeding, and most were in the postmenopausal period. Risk factors for these patients and those with atypical hyperplasia indicated statistically significant positive family history(p=0.037) and estrogen therapy history(p=0.028). Out of 536 oophorectomies, 236 were performed in women under 50.ConclusionThe study highlights the need to implement the current literature and promote minimally invasive approaches. Widespread adoption of non-hysterectomy options is essential for rate reduction. Physicians must integrate current literature, refine skills in minimally invasive methods, and advance surgical techniques to achieve an idealized approach for premalignant lesions and endometrial cancer. Presenting clinic data to personalize algorithms and treatments will strengthen the literature, enhancing the field and increasing the applicability of knowledge for personalized implementation of ideal algorithms and treatments.
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来源期刊
Malawi Medical Journal
Malawi Medical Journal Medicine-General Medicine
CiteScore
1.50
自引率
0.00%
发文量
27
审稿时长
>12 weeks
期刊介绍: Driven and guided by the priorities articulated in the Malawi National Health Research Agenda, the Malawi Medical Journal publishes original research, short reports, case reports, viewpoints, insightful editorials and commentaries that are of high quality, informative and applicable to the Malawian and sub-Saharan Africa regions. Our particular interest is to publish evidence-based research that impacts and informs national health policies and medical practice in Malawi and the broader region. Topics covered in the journal include, but are not limited to: - Communicable diseases (HIV and AIDS, Malaria, TB, etc.) - Non-communicable diseases (Cardiovascular diseases, cancer, diabetes, etc.) - Sexual and Reproductive Health (Adolescent health, education, pregnancy and abortion, STDs and HIV and AIDS, etc.) - Mental health - Environmental health - Nutrition - Health systems and health policy (Leadership, ethics, and governance) - Community systems strengthening research - Injury, trauma, and surgical disorders
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