北印度女性食指和无名指的比例(2D:4D)及其与高血压的相关性,以及它对心血管疾病可能性因素的影响

Sunil Kumar, Sadakat Ali
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摘要

高血压是心血管疾病(CVDs)的主要风险因素,也是全球日益关注的问题。由食指和无名指的相对长度决定的第 2 位数与第 4 位数之比(2D:4D)与产前睾酮暴露和潜在的心血管健康有关。本研究调查了北印度女性人群中 2D:4D 比例与高血压之间的相关性,探索其作为心血管疾病风险因素的潜在作用。这项横断面研究将在北印度女性中进行。参与者将通过社区宣传和医疗机构招募。数据收集将包括1.2.测量血压,以确定高血压患者和血压正常者;3.测量双手第 2 和第 4 指长度,以计算 2D:4D 比例。这项研究有望揭示北印度女性人口中 2D:4D 比例与高血压患病率之间的相关性。我们假设,2D:4D 比率较低的女性(表明产前睾酮暴露较高)可能表现出较高的高血压患病率。这一发现可能表明,产前激素影响与日后心血管疾病风险增加之间存在潜在联系。这项研究的设计是横断面的,无法确定因果关系。要探讨 2D:4D 比率、高血压和心血管疾病发展之间的因果关系,还需要进一步的纵向研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Index finger and ring finger ratio (2D:4D) and it\'s correlation with Hypertension and it\'s affects for possibility factors in cardiovascular diseases in North Indian female population
Hypertension is a major risk factor for cardiovascular diseases (CVDs) and is a growing concern globally. The 2nd to 4th digit ratio (2D:4D), determined by the relative length of the index and ring fingers, has been linked to prenatal testosterone exposure and potentially cardiovascular health. This study investigates the correlation between 2D:4D ratio and hypertension in a North Indian female population, exploring its potential role as a risk factor for CVDs. A cross-sectional study will be conducted among North Indian females. Participants will be recruited through community outreach and healthcare facilities. Data collection will involve: 1. Demographic information; 2. Blood pressure measurement to identify hypertensive and normotensive individuals; 3. Measurement of the 2nd and 4th finger lengths on both hands to calculate the 2D:4D ratio. The study is expected to reveal a correlation between 2D:4D ratio and hypertension prevalence in the North Indian female population. We hypothesize that females with a lower 2D:4D ratio (indicating higher prenatal testosterone exposure) might exhibit a higher prevalence of hypertension. This finding could suggest a potential association between prenatal hormonal influences and increased risk of CVDs in later life. This study design is cross-sectional, and causality cannot be established. Further longitudinal studies would be needed to explore the cause-and-effect relationship between 2D:4D ratio, hypertension, and CVD development.
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