利用微流体系统评估电化学传感器

Q4 Engineering
A. Legassey, A. Fleming, L. Dagostino, T. Bliznakov, R. Gudlavalleti, J. Kondo, F. Papadimitrakopoulos, F. Jain
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引用次数: 0

摘要

本文介绍了利用微流体系统对电化学传感器进行表征和测试的情况。在生物传感器的铂金工作电极上用激光切割了各种几何图案。在这项工作中,设计了一个微流体室,利用蠕动泵使磷酸盐缓冲溶液(PBS)流过传感器,同时改变过氧化氢的浓度。25、50、75 和 100[式中:见正文][式中:见正文]米穿孔和 75[式中:见正文][式中:见正文]米间距的电化学传感器的安培表征显示出最高的灵敏度。这一结果是意料之中的,因为图案化传感器的目的是为平面电极提供三维结构,以便固定葡萄糖氧化酶。今后的工作将包括选择其中一种图案来固定葡萄糖氧化酶,从而实现功能齐全的葡萄糖传感器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of Electrochemical Sensor Using Microfluidic System
This paper presents the characterization and testing of electrochemical sensor using microfluidic system. Various geometric patterns were laser cut into the platinum working electrode of a biosensor. In this work, a microfluidic chamber was designed that allows phosphate buffer solution (PBS) to flow across the sensor, using a peristaltic pump, while varying the concentration of hydrogen peroxide. The amperometric characterization of the electrochemical sensor with 25, 50, 75, and 100[Formula: see text][Formula: see text]m perforation and 75[Formula: see text][Formula: see text]m spacing showed the highest sensitivity. This result was to be expected the purpose of patterning the sensors was to provide a 3-dimensional structure to the planar electrode in order for the enzyme, glucose oxidase, to be immobilized. Future work will include selecting one of the patterns for immobilization of glucose oxidase allowing us to realize a fully functional glucose sensor.
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来源期刊
International Journal of High Speed Electronics and Systems
International Journal of High Speed Electronics and Systems Engineering-Electrical and Electronic Engineering
CiteScore
0.60
自引率
0.00%
发文量
22
期刊介绍: Launched in 1990, the International Journal of High Speed Electronics and Systems (IJHSES) has served graduate students and those in R&D, managerial and marketing positions by giving state-of-the-art data, and the latest research trends. Its main charter is to promote engineering education by advancing interdisciplinary science between electronics and systems and to explore high speed technology in photonics and electronics. IJHSES, a quarterly journal, continues to feature a broad coverage of topics relating to high speed or high performance devices, circuits and systems.
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