手术后横纹肌溶解症

Jessica Cecilia Robles Pérez, Gabriel Sebastián Jaramillo Orellana, Paúl Santiago Martínez Torres
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摘要

导言:横纹肌溶解症是一种发病率较低的术后并发症,其特点是肌坏死并向血液中释放毒素。横纹肌溶解症有诱发因素,大多数手术后横纹肌溶解症的病因是多因素的。目的:本文旨在报告一名外科手术后确诊横纹肌溶解症患者的临床病例,并提供早期诊断和及时治疗的相关信息:该病例是一名 69 岁的男性患者,他接受了肩关节镜手术,修复了因先前和上部损伤导致的肩袖,并进行了肱二头肌腱膜切除术和肩峰锁骨下减压术。术后,他出现气喘、恶心和 12 小时无尿。有证据显示氮质血症和肌肉酶升高(肌酸磷酸激酶(CPK):10,519U/L),横纹肌溶解症诊断成立。除了类固醇(甲基强的松龙)、N-乙酰半胱氨酸和碳酸氢盐外,他还输注了晶体液和呋塞米,但情况没有好转,需要进行血液透析。随后,他的病情发展良好,氮质血症和肌酶逐渐下降,住院 14 天后出院:讨论和结论:手术后横纹肌溶解症通常是一种多因素病理,受到与患者、手术过程和药物直接相关的易感因素的影响。本病例是一例罕见的多因素手术后横纹肌溶解症病例,患者是一名老年男性,被认为是危险因素,需要接受 RRT 治疗,因此增加了住院天数。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postsurgical rhabdomyolysis
Introduction: Rhabdomyolysis is an entity that can present as a low-incidence postoperative complication characterized by myonecrosis with release of toxins into the bloodstream. There are predisposing factors and the majority of post-surgical rhabdomyolysis have a multifactorial etiology. It generally presents with acute kidney injury and the need for dialysis, which increases the days of hospital stay and mortality. Purpose: The purpose of this article is to report on the clinical case of a patient diagnosed with rhabdomyolysis after a surgical intervention, in addition to providing relevant information on early diagnosis and timely treatment. Case presentation: It is about a 69-year-old male patient who undergoes surgery for shoulder arthroscopy, repair of the rotator cuff due to previous and superior injury, plus biceps tenotomy with subdeltoideal acromioclavicular decompression. During the postoperative period, he presents asthenia, nausea, and 12 hours of anuria. There is evidence of elevation in azotemia and muscle enzymes (Creatine phosphokinase (CPK): 10,519U/L), and the diagnosis of rhabdomyolysis is established. He remains hospitalized with an infusion of crystalloids and furosemide, in addition to steroids (methylprednisolone), N-acetylcysteine, and bicarbonate, without improvement, requiring hemodialysis. Subsequently, he evolves favorably with a gradual decrease in azotemia and muscle enzymes, and is discharged after 14 days of hospitalization. Discussion and conclusion: Post-surgical rhabdomyolysis is frequently a multifactorial pathology, influenced by predisposing elements directly related to the patient, the surgical process, and drugs. A rare case of multifactorial postsurgical RML is presented in an elderly male patient, considered as risk factors, who required RRT and therefore, it increased hospitalization´s days.
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