评估将直肠周围硬化剂注射配合 50%葡萄糖注射作为治疗小儿直肠脱垂的主要手术方法的有效性和安全性:临床试验

IF 0.4 4区 医学 Q4 PEDIATRICS
Davoud Badebarin, S. Aslanabadi, Ebrahim Farhadi, Hamed Danaie, Sahand Eslami
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引用次数: 0

摘要

背景:直肠脱垂是指直肠从肛门突出。本研究旨在评估使用 50%葡萄糖注射的直肠周围硬化剂疗法作为 14 岁以下儿童直肠脱垂的主要手术方法的有效性。研究目的本研究的目的是评估使用 50%葡萄糖注射液进行直肠周围硬化剂注射作为治疗儿童直肠脱垂的主要手术方法的有效性、安全性和优势。方法:这项临床试验涉及 40 名被诊断为直肠脱垂的患者,他们都接受了直肠周围硬化剂(50% 葡萄糖)注射治疗。所有患者均为 III 级或 IV 级直肠脱垂。患者取平卧位,在齿状线上方 2 - 3 厘米处的肛门周围和粘膜下注射三次 50%葡萄糖。在肛门周围 3、6 和 9 点钟位置注射(6 点钟位置 1 cc/kg,3 和 9 点钟位置 0.5 cc/kg)。患者分别在三个月和六个月后接受复发和并发症随访。结果患者平均年龄为 5.62 岁,大多数为男性(77.5%)。从症状出现到实施硬化疗法的平均时间为 6.60±1.73 个月。五名患者在观察的第一天出现了肛门周围和注射部位水肿。第二次检查(一周后)时,只有一名患者出现蜂窝组织炎。在三个月的检查中,有八名患者出现了直肠粘液流出的症状,这被视为中期并发症。在六个月的最后一次检查中,有四名患者出现脱垂复发。结论:根据研究结果,可以得出结论:使用 50%葡萄糖注射液进行直肠周围硬化疗法是治疗 14 岁以下儿童直肠脱垂的一种有效的初级手术方法。与开腹手术相比,该疗法简单、费用低廉、并发症风险小、恢复时间短。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating the Efficacy and Safety of Perirectal Sclerotherapy with 50% Dextrose Injection as a Primary Surgical Procedure for Rectal Prolapse in Pediatric Patients: A Clinical Trial
Background: Rectal prolapse is a condition where the rectum protrudes through the anus. This study aimed to evaluate the effectiveness of perirectal sclerotherapy using a 50% dextrose injection as a primary surgical procedure for rectal prolapse in children under 14 years of age. Objectives: The purpose of the study was to evaluate the efficacy, safety, and advantages of perirectal sclerotherapy using a 50% dextrose injection as a primary surgical procedure for rectal prolapse in pediatric patients. Methods: This clinical trial involved 40 patients diagnosed with rectal prolapse, who were treated with perirectal sclerosant (dextrose 50%) injection. All patients had grade III or grade IV rectal prolapse. Three injections of 50% dextrose were administered into the area around the anus and the submucosa, 2 - 3 cm above the dentate line, while the patient was in the lithotomy position. Injections were given at the 3, 6, and 9 o'clock positions around the anus (1 cc/kg at the 6 o'clock position and 0.5 cc/kg at the 3 and 9 o'clock positions). The patients were followed up for recurrence and complications at three-month and six-month intervals, respectively. Results: The patients had an average age of 5.62 years, with the majority being male (77.5%). The average time between symptom onset and sclerotherapy administration was 6.60 ± 1.73 months. Five patients experienced edema around the anus and injection site on the first day of observation. At the second examination (one week later), only one patient had cellulitis. At the three-month visit, eight patients exhibited symptoms of rectal mucus discharge, which were considered mid-term complications. In the final examination at six months, four patients experienced prolapse recurrences. Conclusions: Based on the findings, it can be concluded that perirectal sclerotherapy using a 50% dextrose injection is an effective primary surgical procedure for rectal prolapse in children under 14 years of age. The treatment is simple, inexpensive, and associated with minimal risk of complications and short recovery times compared to open surgery.
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来源期刊
CiteScore
0.90
自引率
20.00%
发文量
75
审稿时长
6-12 weeks
期刊介绍: Iranian Journal of Pediatrics (Iran J Pediatr) is a peer-reviewed medical publication. The purpose of Iran J Pediatr is to increase knowledge, stimulate research in all fields of Pediatrics, and promote better management of pediatric patients. To achieve the goals, the journal publishes basic, biomedical, and clinical investigations on prevalent diseases relevant to pediatrics. The acceptance criteria for all papers are the quality and originality of the research and their significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by minimum three anonymous reviewers. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as the material cannot be returned. Final acceptance or rejection rests with the Editors.
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