含有葡甘露聚糖和木薯淀粉的新型魔芋米配方可改善餐后血糖反应--随机单盲临床试验

Yufita Ratnasari Wilianto, Yudy Tjahjono, K. Foe, Sumi Wijaya, Martha Ervina, Diga Albrian Setiadi, Hevi Wihadmadyatami, Bernadette Dian Novita Dewi, Hendy Wijaya
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This study aims to investigate whether a KR formula, combining tapioca flour and glucomannan gel, possesses similar organoleptic attributes to white rice while preventing glycemic response elevation.\n\nDesign/methodology/approach\nIn a six-week randomized single-blind clinical trial, 13 normoweight nondiabetic subjects received varying konjac-based rice and white rice ratios. Blood glucose levels were measured at intervals, and glycemic response was assessed using incremental area under the curve (iAUC). Visual analog scale gauged satiety, and organoleptic properties were evaluated.\n\nFindings\nSubstituting white rice with pure and partial konjac-based rice significantly lowered postprandial blood sugar levels and glycemic response (p = 0.002). iAUC for pure KR and KR 1:1 was notably lower than white rice (p = 0.002). 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引用次数: 0

摘要

目的在许多亚洲国家,由于白米与糖尿病和其他慢性疾病有关,许多行业都在努力开发具有类似感官特征的高纤维大米替代品。魔芋米(Konjac rice,KR)是一种很有前景的选择,但在保持其理想感官特征的同时,如何保持其最佳纤维含量以获得健康益处仍是一项挑战。本研究旨在调查一种结合了木薯粉和葡甘露聚糖凝胶的 KR 配方是否具有与白米饭相似的感官特性,同时防止血糖反应升高。设计/方法/方法在一项为期六周的随机单盲临床试验中,13 名体重正常的非糖尿病受试者接受了不同比例的魔芋米饭和白米饭。每隔一段时间测量血糖水平,并使用曲线下面积增量法(iAUC)评估血糖反应。用纯魔芋大米和部分魔芋大米代替白米饭可显著降低餐后血糖水平和血糖反应(p = 0.002)。纯魔芋大米和魔芋大米 1:1 的 iAUC 明显低于白米饭(p = 0.002)。受试者报告的饱腹感与白米饭相当,没有明显的感官评分差异(p = 0.260)。研究局限性/意义由于参与人数有限,研究的普遍性受到影响,影响了外部有效性。研究参数提供了魔芋谷物对餐后血糖反应影响的粗略认识,但并未阐明其潜在机制或抑制葡萄糖吸收作用的持续时间。对代谢、激素参数和结肠微生物菌群组成及功能的长期影响仍未探明,这限制了对魔芋谷物延伸意义的全面了解。用魔芋谷物代替白米饭可明显降低餐后血糖水平,突出了其在预防 2 型糖尿病(T2D)方面的潜力。木薯粉提高了适口性,使 KR 成为一种可行的选择。虽然前景广阔,但长期有效性和安全性还需要进一步研究,并强调全面的生活方式干预。社会影响白米饭是亚洲社会的主食,由于产量增加和膳食纤维不足,白米饭与罹患 T2D 的风险增加有关。这种联系通过医疗保险和生产力损失加重了政府的经济负担。鼓励使用富含纤维的替代品可以减轻这种负担,为可预防的慢性疾病提供一个有益于社会经济的解决方案。试验还强调了葡甘聚糖的粘度、饱腹感和对肠道健康的潜在影响。关于其长期有效性和安全性,还需要进一步研究。这些发现为越来越多的证据支持葡甘聚糖作为解决普遍健康问题的宝贵工具做出了贡献。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A novel konjac rice formula with glucomannan and tapioca starch improve postprandial glycemic response – a randomized single-blind clinical trial
Purpose Due to white rice’s association with diabetes and other chronic diseases in many Asian countries, many industries are working to develop high-fiber rice substitutes with similar organoleptic characteristics. Konjac rice (KR) is a promising option, but maintaining its optimal fiber content for health benefits while preserving its ideal sensory profile remains a challenge. This study aims to investigate whether a KR formula, combining tapioca flour and glucomannan gel, possesses similar organoleptic attributes to white rice while preventing glycemic response elevation. Design/methodology/approach In a six-week randomized single-blind clinical trial, 13 normoweight nondiabetic subjects received varying konjac-based rice and white rice ratios. Blood glucose levels were measured at intervals, and glycemic response was assessed using incremental area under the curve (iAUC). Visual analog scale gauged satiety, and organoleptic properties were evaluated. Findings Substituting white rice with pure and partial konjac-based rice significantly lowered postprandial blood sugar levels and glycemic response (p = 0.002). iAUC for pure KR and KR 1:1 was notably lower than white rice (p = 0.002). Subjects reported a sense of fullness comparable to white rice, with no significant organoleptic score differences (p = 0.260). Research limitations/implications The study’s generalizability is compromised due to the limited number of participants, impacting external validity. The examined parameters offer a rough understanding of konjac grain’s impact on postprandial glycemic responses but do not elucidate underlying mechanisms or the duration of its inhibitory effect on glucose absorption. Long-term effects on metabolic, hormonal parameters and the colon’s microbial flora composition and function remain unexplored, constraining comprehensive insights into konjac grain’s extended implications. Practical implications This study introduces a novel KR formula to address the escalating diabetes risks associated with white rice consumption. Substituting white rice with KR significantly reduces postprandial blood sugar levels, highlighting its potential in preventing type 2 diabetes (T2D). Tapioca flour enhances palatability, making KR a viable option. While promising, long-term effectiveness and safety require further research, emphasizing comprehensive lifestyle interventions. The study contributes valuable insights to innovative dietary strategies for prevalent health conditions, emphasizing the need for ongoing efforts in public health. Social implications White rice, a staple in Asian societies, is linked to a heightened risk of T2D due to increased production and inadequate dietary fiber. This connection contributes to the economic burden on governments through health insurance and lost productivity. Encouraging alternatives rich in fiber can mitigate this burden, offering a socioeconomically beneficial solution to preventable chronic diseases. Originality/value This trial demonstrates konjac-based rice’s potential in curbing glycemic responses, hinting at its role in preventing T2D. Glucomannan’s viscosity, satiety induction and potential gut health impact are highlighted. Further research is warranted for long-term effectiveness and safety. These findings contribute to the growing evidence supporting glucomannan as a valuable tool in addressing prevalent health conditions.
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