评估腹痛儿科患者的铅中毒患病率及相关因素

IF 0.4 4区 医学 Q4 PEDIATRICS
Abbas Avazpour, Farrokhnaz Abbasian, Amir Hossein Hassani, Sara Matin
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引用次数: 0

摘要

背景:铅中毒是一种自古以来就存在的环境疾病,可表现为腹痛、便秘或神经功能障碍等症状。在环境疾病中,铅中毒造成的负担最重。研究目的本研究旨在评估伊朗南部腹痛患者的铅中毒患病率。研究方法在这项研究中,比较了 50 名慢性腹痛儿科患者和 50 名健康人的血铅水平以及可能导致铅中毒的基本人口信息。结果本研究共招募了 100 名参与者,平均年龄为(8.50 ± 2.444)岁,其中 53.0% 为男性。对照组和病例组的平均血铅水平分别为 1.54 ± 0.693 µg/dL 和 2.73 ± 2.547 µg/dL,差异有统计学意义(P = 0.002)。当考虑铅中毒的临界值为 2 µg/dL 和 3.5 µg/dL 时,病例组的铅中毒发生率明显更高。铅中毒患者与铅含量正常的患者在环境和人口因素方面没有差异(P > 0.05)。结论在主诉慢性腹痛的儿童中,铅中毒的发病率为 12.0%(95% CI:4.5% - 24.3%)。然而,在今后的研究中需要对环境进行更精确的检测。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessing the Prevalence of Lead Toxicity and Related Factors in Pediatric Patients with Abdominal Pain
Background: Lead toxicity is an environmental disease that has been encountered since ancient times and can present with symptoms such as abdominal pain, constipation, or neurological deficits. This issue accounts for the highest burden among environmental disorders. Objectives: The aim of this study was to assess the prevalence of lead toxicity in patients with abdominal pain in Southern Iran. Methods: In this study, 50 pediatric patients with chronic abdominal pain and 50 healthy individuals were compared in terms of their blood lead levels and underlying demographic information that could contribute to lead toxicity. Results: A total of 100 participants were enrolled in this study, with a mean age of 8.50 ± 2.444 years, 53.0% of whom were male. The mean blood lead levels in the control and case groups were 1.54 ± 0.693 and 2.73 ± 2.547 µg/dL, respectively, with a statistically significant difference (P = 0.002). When cutoff values of 2 µg/dL and 3.5 µg/dL were considered for lead toxicity, the prevalence of lead toxicity was significantly higher in the case group. Environmental and demographic factors did not differ between patients with lead toxicity and those with normal lead levels (P > 0.05). Conclusions: The prevalence of lead toxicity in children complaining of chronic abdominal pain was 12.0% (95% CI: 4.5% - 24.3%). However, more accurate testing of the environment is needed in future studies.
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来源期刊
CiteScore
0.90
自引率
20.00%
发文量
75
审稿时长
6-12 weeks
期刊介绍: Iranian Journal of Pediatrics (Iran J Pediatr) is a peer-reviewed medical publication. The purpose of Iran J Pediatr is to increase knowledge, stimulate research in all fields of Pediatrics, and promote better management of pediatric patients. To achieve the goals, the journal publishes basic, biomedical, and clinical investigations on prevalent diseases relevant to pediatrics. The acceptance criteria for all papers are the quality and originality of the research and their significance to our readership. Except where otherwise stated, manuscripts are peer-reviewed by minimum three anonymous reviewers. The Editorial Board reserves the right to refuse any material for publication and advises that authors should retain copies of submitted manuscripts and correspondence as the material cannot be returned. Final acceptance or rejection rests with the Editors.
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