接受血液透析治疗的慢性肾病患者的生活质量:印度西部的一项横断面研究

Drashti D. Shah, Venu R. Shah, Viral R. Dave
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摘要

导言:血液透析是延长慢性肾病(CKD)患者生命的最常用疗法。研究他们的生活质量(QoL)可为医疗决策者提供有价值的信息。研究目的评估接受血液透析的 CKD 患者的 QoL 及其影响因素:随机选取印度古吉拉特邦艾哈迈达巴德市的两家透析中心的 200 名血液透析患者进行横断面研究。研究采用连续抽样的方法招募患者。评估 QoL 时使用了经过验证的调查问卷,包括肾病生活质量 - 短表™ 1.3 版(KDQOL-SF™ v1.3)。计算了包括肾病(KDCS)、身体(PCS)和精神(MCS)在内的成分总和(CS)的平均得分。使用 Kruskal Wallis 方差分析和 Mann Whitney U 检验比较 CS 中位数得分,找出影响 QoL 的因素。结果参与者的平均年龄为 55.65 岁(SD=12.56),女性占 42%。KDCS、PCS 和 MCS 的平均(标清)得分分别为 70.49 (9.04)、57.21 (23.21) 和 65.31 ( 15.26)。平均(标清)得分最高的是 "透析工作人员鼓励 "96.25(8.4)分,其次是 "社会支持 "91.5(19.55)分和认知功能 88.33(13.37)分。肾病负担 17.62 (25.12)、工作状况 40 (32.48) 和身体健康造成的角色限制 47.87 (47.73) 分值最低。年龄超过 50 岁的患者以及同时患有糖尿病和高血压的患者在所有三个 QoL 要素中的得分都明显较低(P<0.01)。其他重要因素包括教育程度和职业。结论与建议:肾脏疾病和精神部分的 QoL 评分优于身体部分。影响 QoL 的因素包括年龄、教育程度、职业和合并症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Quality of life among patients undergoing haemodialysis for chronic kidney disease: a cross-sectional study from Western India
Introduction: Haemodialysis is the most often utilised therapy for  extending life of chronic kidney disease (CKD) patients. Studying their quality of life (QoL) can offer valuable insi ghts for healthcare policy makers. Objectives: To assess the QoL and factors influencing it among CK D patients undergoing haemodialysis Methods: A cross-sectional study was conducted among 200 patient s undergoing haemodialysis at randomly selected two dialysis centres of Ahmedabad City of Gujarat, India. They were  recruited using consecutive sampling method. A validated questionnaire including the Kidney Disease Quality of Life -Short Form™ version 1.3 (KDQOL-SF™ v1.3) was used to assess the QoL. Average scores for Component Summar y (CS) including kidney disease (KDCS), physical (PCS) and mental (MCS) were calculated. Factors influencing the Q oL were identified by comparing median CS scores using Kruskal Wallis ANOVA and Mann Whitney U test. Results: The mean age of participants was 55.65 (SD=12.56) yea rs and 42% were females. Mean (SD) score for KDCS, PCS and MCS were 70.49 (9.04), 57.21 (23.21) and 65.31 ( 15.26), respectively. The highest mean (SD) score was for ‘dialysis staff encouragement’ 96.25 (8.4) followed by ‘social support’ 91.5 (19.55) and cognitive function 88.33 (13.37). The burden of kidney disease 17.62 (25.12), work  status 40 (32.48) and role limitation caused by physical health 47.87 (47.73) had the lowest scores. Patients ≥ 50 ye ars and those diagnosed with both diabetes and hypertension, demonstrated markedly lower scores (p<0.01) across al l three QoL components. Other significant factors were education and occupation. Conclusions & Recommendations: Kidney diseases and mental c omponent QoL scores were better compared to physical component. Factors influencing QoL were age, education, oc cupation and comorbidities.
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