{"title":"口咽念珠菌病--儿童医学的跨学科问题","authors":"S.O. Mokia-Serbina, V.I. Fesenko","doi":"10.22141/2224-0551.19.4.2024.1711","DOIUrl":null,"url":null,"abstract":"Scientific research in recent years has increased the interest of clinicians in the role of microorganisms in maintaining health and the occurrence of diseases. In most cases, fungal lesions of the oral mucosa are a manifestation of numerous somatic diseases and the results of their treatment and contribute to complications. To write this article, the information was searched using the databases Scopus, Web of Science, Med Zine, Pub Med, Google Scholar, the new version of the International Classification of Diseases (ICD-11) and the Standards of Care “Rational use of antibacterial and antifungal drugs for therapeutic and prophylactic purposes” (2023) were taken into account. The review presents data from the world literature on the role of fungal infection in the development of oropharyngeal candidiasis in children, current perspectives on the mechanism of its formation, clinical manifestations and diagnosis. A comparative characterization of the recommendations of national and foreign guidelines and a generalization of retrospective analyzes on the feasibility of prescribing systemic antifungal drugs for candidal lesions of the oral mucosa and possible methods of correction for mycoecological disorders in children are given. In the context of the presented problem, an integrated approach of a primary care physician, dentist and pediatrician to the diagnosis and treatment of oropharyngeal candidiasis in children is recommended. Timely diagnosis of oropharyngeal candidiasis in children, individual selection of antifungal drugs, synbiotics and multicomponent agents based on probiotics should be a priority area of joint work of general practitioners — family physicians, pediatricians and dentists.","PeriodicalId":338009,"journal":{"name":"CHILD`S HEALTH","volume":"4 4","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Oropharyngeal candidiasis — interdisciplinary aspects of childhood medicine\",\"authors\":\"S.O. Mokia-Serbina, V.I. Fesenko\",\"doi\":\"10.22141/2224-0551.19.4.2024.1711\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Scientific research in recent years has increased the interest of clinicians in the role of microorganisms in maintaining health and the occurrence of diseases. In most cases, fungal lesions of the oral mucosa are a manifestation of numerous somatic diseases and the results of their treatment and contribute to complications. To write this article, the information was searched using the databases Scopus, Web of Science, Med Zine, Pub Med, Google Scholar, the new version of the International Classification of Diseases (ICD-11) and the Standards of Care “Rational use of antibacterial and antifungal drugs for therapeutic and prophylactic purposes” (2023) were taken into account. The review presents data from the world literature on the role of fungal infection in the development of oropharyngeal candidiasis in children, current perspectives on the mechanism of its formation, clinical manifestations and diagnosis. A comparative characterization of the recommendations of national and foreign guidelines and a generalization of retrospective analyzes on the feasibility of prescribing systemic antifungal drugs for candidal lesions of the oral mucosa and possible methods of correction for mycoecological disorders in children are given. In the context of the presented problem, an integrated approach of a primary care physician, dentist and pediatrician to the diagnosis and treatment of oropharyngeal candidiasis in children is recommended. Timely diagnosis of oropharyngeal candidiasis in children, individual selection of antifungal drugs, synbiotics and multicomponent agents based on probiotics should be a priority area of joint work of general practitioners — family physicians, pediatricians and dentists.\",\"PeriodicalId\":338009,\"journal\":{\"name\":\"CHILD`S HEALTH\",\"volume\":\"4 4\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"CHILD`S HEALTH\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22141/2224-0551.19.4.2024.1711\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"CHILD`S HEALTH","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22141/2224-0551.19.4.2024.1711","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
近年来的科学研究提高了临床医生对微生物在维持健康和疾病发生中的作用的兴趣。在大多数情况下,口腔黏膜真菌病变是多种躯体疾病的一种表现形式,也是其治疗的结果和并发症的诱因。为撰写本文,我们使用 Scopus、Web of Science、Med Zine、Pub Med、Google Scholar 等数据库进行了信息检索,并参考了新版《国际疾病分类》(ICD-11)和《合理使用抗菌和抗真菌药物进行治疗和预防》(2023 年)护理标准。综述介绍了世界文献中关于真菌感染在儿童口咽念珠菌病发病中的作用、其形成机制、临床表现和诊断的最新观点。此外,还对国内外指南的建议进行了比较分析,并对口腔黏膜念珠菌病变处方全身抗真菌药物的可行性进行了回顾性分析,以及对儿童霉菌性生态失调的可能矫正方法进行了归纳总结。针对所提出的问题,建议采用由初级保健医生、牙医和儿科医生共同参与的综合方法来诊断和治疗儿童口咽念珠菌病。及时诊断儿童口咽念珠菌病,单独选择抗真菌药物、合生素和基于益生菌的多成分制剂,应成为全科医生--家庭医生、儿科医生和牙科医生联合工作的优先领域。
Oropharyngeal candidiasis — interdisciplinary aspects of childhood medicine
Scientific research in recent years has increased the interest of clinicians in the role of microorganisms in maintaining health and the occurrence of diseases. In most cases, fungal lesions of the oral mucosa are a manifestation of numerous somatic diseases and the results of their treatment and contribute to complications. To write this article, the information was searched using the databases Scopus, Web of Science, Med Zine, Pub Med, Google Scholar, the new version of the International Classification of Diseases (ICD-11) and the Standards of Care “Rational use of antibacterial and antifungal drugs for therapeutic and prophylactic purposes” (2023) were taken into account. The review presents data from the world literature on the role of fungal infection in the development of oropharyngeal candidiasis in children, current perspectives on the mechanism of its formation, clinical manifestations and diagnosis. A comparative characterization of the recommendations of national and foreign guidelines and a generalization of retrospective analyzes on the feasibility of prescribing systemic antifungal drugs for candidal lesions of the oral mucosa and possible methods of correction for mycoecological disorders in children are given. In the context of the presented problem, an integrated approach of a primary care physician, dentist and pediatrician to the diagnosis and treatment of oropharyngeal candidiasis in children is recommended. Timely diagnosis of oropharyngeal candidiasis in children, individual selection of antifungal drugs, synbiotics and multicomponent agents based on probiotics should be a priority area of joint work of general practitioners — family physicians, pediatricians and dentists.