罗非鱼（Oreochromis Niloticus）幼鱼过氧化氢酶活性、鳃组织学和镉的遗传毒性效应评估

IF 0.7 4区综合性期刊 Q3 MULTIDISCIPLINARY SCIENCES

Sains Malaysiana Pub Date : 2024-07-31 DOI:10.17576/jsm-2024-5307-01

Amna Marium, Huma Naz, Tanveer Ahmed, Muhammad Umar Ijaz, Muhammad Usman, Zahid Manzoor, Basharat Ali, Awatif Omran, Yasmene F. Alanazi, Rasha M.A. Jame, Ayman El Sabagh

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引用次数: 0

摘要

本研究旨在评估镉（Cd）的毒性及其对黑线鲈过氧化氢酶（CAT）活性、鳃组织学和遗传毒性的影响。采用 Probit 方法计算出镉对鱼类的急性毒性（96 小时）为 56.021 毫克/升（LC50）和 80.7336 毫克/升（LC100）。推断结果表明，与无金属应激的对照组相比，经镉处理的黑线鳕体内过氧化氢酶水平明显降低（P<0.05）。其顺序为：肠<鳃<肌肉<脑。鳃组织学研究结果表明，镉暴露对初级和次级薄片都造成了严重破坏。组织学改变包括次生薄片融合和卷曲、次生薄片增生、上皮抬升以及鳃中观察到的动脉瘤。基因毒性结果显示，与对照组相比，暴露于镉的尼罗河鲑红细胞中的微核、去形核和缺口核显著增加（p<0.05）。本研究的推论证实了镉的基因毒性。这项研究将有助于了解镉胁迫下鱼体的组织学和基因毒性变化。这项研究还有助于制定具体的方法，最大限度地减少镉的负面影响和基因毒性。此外，罗非鱼还可作为一种良好的生物指标，用于检测与水污染有关的毒性影响。

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Evaluation of Catalase Activity, Gill Histology and Genotoxic Effects of Cadmium in Tilapia (Oreochromis Niloticus) Fingerlings

This research was designed to assess the toxicity of cadmium (Cd), and its effects on catalase (CAT) activity, histology of gills and geno-toxicity of Oreochromis niloticus. The acute toxicity of Cd (96-h) for fish was computed as 56.021 mg/L (LC50) and 80.7336 mg/L (LC100) using Probit method. The inferences showed that catalase level was significantly (P<0.05) lower in Cd treated O. niloticus as compared to control that was metal-stress free. It followed the order as: intestine

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来源期刊

Sains Malaysiana MULTIDISCIPLINARY SCIENCES-

CiteScore

1.60

自引率

12.50%

发文量

196

审稿时长

3-6 weeks

期刊介绍： Sains Malaysiana is a refereed journal committed to the advancement of scholarly knowledge and research findings of the several branches of science and technology. It contains articles on Earth Sciences, Health Sciences, Life Sciences, Mathematical Sciences and Physical Sciences. The journal publishes articles, reviews, and research notes whose content and approach are of interest to a wide range of scholars. Sains Malaysiana is published by the UKM Press an its autonomous Editorial Board are drawn from the Faculty of Science and Technology, Universiti Kebangsaan Malaysia. In addition, distinguished scholars from local and foreign universities are appointed to serve as advisory board members and referees.

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