无声的威胁揭开开胸手术后低氧血症的神秘面纱

Abdullah Khalid, Hamdan Mallick, Muhammad Yasir Khan, Shiraz Hashmi, Syed Shahabuddin
{"title":"无声的威胁揭开开胸手术后低氧血症的神秘面纱","authors":"Abdullah Khalid, Hamdan Mallick, Muhammad Yasir Khan, Shiraz Hashmi, Syed Shahabuddin","doi":"10.1101/2024.07.25.24311019","DOIUrl":null,"url":null,"abstract":"Introduction:\nHypoxemia is a well-known postoperative complication following open heart surgery. There is minimal literature and a lack of consensus on postoperative hypoxemia as a complication following open heart surgery and its relation to adverse outcomes, risk factors, and population characteristics. This is especially more apparent in lower middle-income countries where there is a double burden of disease. We aimed to determine the predictive and risk factors for postoperative hypoxemia due to the high incidence of associated complications that include increased morbidity, mortality, and length of hospital stay.\nMethods:\nThis study was a retrospective analysis, evaluating first-time open-heart surgery patients over a period of one year from January to December 2020. Data was collected prospectively through the section of cardiothoracic surgery computerized database, using standardized data collection strategies and definitions. Results:\nThe overall prevalence of hypoxemia was estimated to be 73 (11.8%). Morbidity and Mortality were significantly higher in the hypoxemic group. Male gender, diabetes, hypertension, low EF%, CBP time, increased preoperative PaCO2, were found to be independent risk factors for the development of hypoxemia. Conclusion:\nFrom the results of this study, it could be concluded that the magnitude of hypoxemia is substantial after on-pump open heart surgery. High-risk and independent factors identified from this study were cumulatively grouped and preventive use of BiPAP was found to be a possible option to prevent hypoxemia This study highlights the importance of one of the underestimated post-op morbid factors with cost, quality, and outcome implications.","PeriodicalId":501051,"journal":{"name":"medRxiv - Surgery","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2024-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Silent Threat: Unveiling the Mystery of Post Op Hypoxemia after Open Heart Surgery\",\"authors\":\"Abdullah Khalid, Hamdan Mallick, Muhammad Yasir Khan, Shiraz Hashmi, Syed Shahabuddin\",\"doi\":\"10.1101/2024.07.25.24311019\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Introduction:\\nHypoxemia is a well-known postoperative complication following open heart surgery. There is minimal literature and a lack of consensus on postoperative hypoxemia as a complication following open heart surgery and its relation to adverse outcomes, risk factors, and population characteristics. This is especially more apparent in lower middle-income countries where there is a double burden of disease. We aimed to determine the predictive and risk factors for postoperative hypoxemia due to the high incidence of associated complications that include increased morbidity, mortality, and length of hospital stay.\\nMethods:\\nThis study was a retrospective analysis, evaluating first-time open-heart surgery patients over a period of one year from January to December 2020. Data was collected prospectively through the section of cardiothoracic surgery computerized database, using standardized data collection strategies and definitions. Results:\\nThe overall prevalence of hypoxemia was estimated to be 73 (11.8%). Morbidity and Mortality were significantly higher in the hypoxemic group. Male gender, diabetes, hypertension, low EF%, CBP time, increased preoperative PaCO2, were found to be independent risk factors for the development of hypoxemia. Conclusion:\\nFrom the results of this study, it could be concluded that the magnitude of hypoxemia is substantial after on-pump open heart surgery. High-risk and independent factors identified from this study were cumulatively grouped and preventive use of BiPAP was found to be a possible option to prevent hypoxemia This study highlights the importance of one of the underestimated post-op morbid factors with cost, quality, and outcome implications.\",\"PeriodicalId\":501051,\"journal\":{\"name\":\"medRxiv - Surgery\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"medRxiv - Surgery\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1101/2024.07.25.24311019\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.07.25.24311019","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

导言:低氧血症是众所周知的开胸手术术后并发症。关于开胸手术术后低氧血症并发症及其与不良后果、风险因素和人群特征的关系,目前文献极少,也缺乏共识。这一点在中低收入国家尤为明显,因为这些国家存在双重疾病负担。我们的目的是确定术后低氧血症的预测因素和风险因素,因为相关并发症的发生率很高,包括发病率、死亡率和住院时间的延长。方法:本研究是一项回顾性分析,评估了2020年1月至12月一年内首次接受开胸手术的患者。数据通过心胸外科计算机数据库收集,采用标准化的数据收集策略和定义。结果:低氧血症的总发病率估计为 73 例(11.8%)。低氧血症组的发病率和死亡率明显较高。男性、糖尿病、高血压、低EF%、CBP时间、术前PaCO2升高是低氧血症发生的独立风险因素。结论:从本研究的结果中可以得出结论,泵上开放式心脏手术后低氧血症的发生率很高。本研究对发现的高危因素和独立因素进行了累积分组,发现预防性使用 BiPAP 是预防低氧血症的一种可能选择。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Silent Threat: Unveiling the Mystery of Post Op Hypoxemia after Open Heart Surgery
Introduction: Hypoxemia is a well-known postoperative complication following open heart surgery. There is minimal literature and a lack of consensus on postoperative hypoxemia as a complication following open heart surgery and its relation to adverse outcomes, risk factors, and population characteristics. This is especially more apparent in lower middle-income countries where there is a double burden of disease. We aimed to determine the predictive and risk factors for postoperative hypoxemia due to the high incidence of associated complications that include increased morbidity, mortality, and length of hospital stay. Methods: This study was a retrospective analysis, evaluating first-time open-heart surgery patients over a period of one year from January to December 2020. Data was collected prospectively through the section of cardiothoracic surgery computerized database, using standardized data collection strategies and definitions. Results: The overall prevalence of hypoxemia was estimated to be 73 (11.8%). Morbidity and Mortality were significantly higher in the hypoxemic group. Male gender, diabetes, hypertension, low EF%, CBP time, increased preoperative PaCO2, were found to be independent risk factors for the development of hypoxemia. Conclusion: From the results of this study, it could be concluded that the magnitude of hypoxemia is substantial after on-pump open heart surgery. High-risk and independent factors identified from this study were cumulatively grouped and preventive use of BiPAP was found to be a possible option to prevent hypoxemia This study highlights the importance of one of the underestimated post-op morbid factors with cost, quality, and outcome implications.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信