采用顺序估计调整瓮模型的自适应无缝二期/三期设计

IF 0.8 4区数学 Q3 STATISTICS & PROBABILITY

Communications in Statistics-Simulation and Computation Pub Date : 2024-07-22 DOI:10.1080/03610918.2024.2381077

Hongjian Zhu, Jun Yu, Qin Wang, Dejian Lai, Li Wang, Sheng Zhong

引用次数: 0

摘要

临床试验是药物开发过程的重要组成部分，可提供有关新疗法疗效和安全性的关键数据。然而，传统的临床试验设计可能会对新药的疗效和安全性产生不利影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Adaptive seamless phase II/III design with sequential estimation-adjusted urn model

Clinical trials are an essential component of the drug development process, providing crucial data on the efficacy and safety of new treatments. However, traditional clinical trial designs can be i...

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来源期刊

Communications in Statistics-Simulation and Computation 数学-统计学与概率论

CiteScore

2.50

自引率

11.10%

发文量

240

审稿时长

6 months

期刊介绍： The Simulation and Computation series intends to publish papers that make theoretical and methodological advances relating to computational aspects of Probability and Statistics. Simulational assessment and comparison of the performance of statistical and probabilistic methods will also be considered for publication. Papers stressing graphical methods, resampling and other computationally intensive methods will be particularly relevant. In addition, special issues dedicated to a specific topic of current interest will also be published in this series periodically, providing an exhaustive and up-to-date review of that topic to the readership.