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引用次数: 0
摘要
摘要:围产期抑郁症(PND)和围产期焦虑症是妊娠期间或之后可能出现的常见疾病,会对患者及其家庭产生重大影响。围产期抑郁症的潜在后果包括自杀死亡,这是孕产妇死亡的一个主要原因。本文概述了这些病症,包括对神经生物学、风险因素、有自杀和/或伤害婴儿风险的个体的警示信号以及相关筛查工具的讨论。文章强调了心理治疗和药物治疗的注意事项,并概述了神经活性类固醇γ-氨基丁酸 A 受体正异位调节剂,这是治疗产后抑郁症的一种较新的药物疗法。
Abstract: Perinatal depression (PND) and perinatal anxiety are common conditions that can arise during or after pregnancy and can have a major impact on patients and their families. A potential outcome of PND includes death by suicide, a leading cause of maternal mortality. This article provides an overview of these conditions, including discussion of neurobiology, risk factors, warning signs for individuals at risk for suicide and/or infant harm, and relevant screening tools. Considerations for psychotherapy and pharmacotherapy are highlighted, and an overview of neuroactive steroid gamma-aminobutyric acid A receptor positive allosteric modulators, a newer pharmacologic treatment option for postpartum depression, is provided.
期刊介绍:
With a circulation of 20,000, The Nurse Practitioner is the leading monthly source for clinical, practical, cutting-edge information for advanced practice nurses and other primary care clinicians. Each issue presents peer-reviewed articles that range from clinical topics and research to political and practice issues. In addition, The Nurse Practitioner provides regular features, columns, continuing education, staff development education, and more.