{"title":"[18F]FDG正电子发射计算机断层显像/磁共振成像（PET/MRI）显示脊髓弥漫性淋巴瘤受累。","authors":"Chunyan Zhao, Liqian Yu, Lin Li, Minggang Su","doi":"10.5603/nmr.99771","DOIUrl":null,"url":null,"abstract":"<p><p>A 61-year-old woman with diffuse large B-cell lymphoma received a fluorine-18-deoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) for staging. Because of the obvious uptake of [¹⁸F]FDG in the spinal cord and brain, a positron emission tomography/magnetic resonance imaging (PET/MRI) was performed after the positron emission tomography/computed tomography (PET/CT). The images showed diffuse [¹⁸F]FDG uptake of the spinal cord and increased T2 signal intensity on MRI, which was suspected to be lymphoma involvement. The patient was diagnosed with diffuse large B-cell lymphoma involving the right maxillofacial region, right cervical lymph nodes, cervix, brain and spinal cord (stage IV of non-germinal center B-cell origin). After chemotherapy, the spinal [¹⁸F]FDG uptake level decreased significantly, which was considered to be a partial metabolic response. Our case was different from prior, which indicated the pattern of spinal cord involvement by lymphoma was focal.</p>","PeriodicalId":44718,"journal":{"name":"NUCLEAR MEDICINE REVIEW","volume":null,"pages":null},"PeriodicalIF":0.6000,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Diffuse lymphoma involvement of the spinal cord showed on [18F]FDG PET/MRI.\",\"authors\":\"Chunyan Zhao, Liqian Yu, Lin Li, Minggang Su\",\"doi\":\"10.5603/nmr.99771\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>A 61-year-old woman with diffuse large B-cell lymphoma received a fluorine-18-deoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) for staging. Because of the obvious uptake of [¹⁸F]FDG in the spinal cord and brain, a positron emission tomography/magnetic resonance imaging (PET/MRI) was performed after the positron emission tomography/computed tomography (PET/CT). The images showed diffuse [¹⁸F]FDG uptake of the spinal cord and increased T2 signal intensity on MRI, which was suspected to be lymphoma involvement. The patient was diagnosed with diffuse large B-cell lymphoma involving the right maxillofacial region, right cervical lymph nodes, cervix, brain and spinal cord (stage IV of non-germinal center B-cell origin). After chemotherapy, the spinal [¹⁸F]FDG uptake level decreased significantly, which was considered to be a partial metabolic response. Our case was different from prior, which indicated the pattern of spinal cord involvement by lymphoma was focal.</p>\",\"PeriodicalId\":44718,\"journal\":{\"name\":\"NUCLEAR MEDICINE REVIEW\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.6000,\"publicationDate\":\"2024-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NUCLEAR MEDICINE REVIEW\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5603/nmr.99771\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NUCLEAR MEDICINE REVIEW","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5603/nmr.99771","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
一名患有弥漫大 B 细胞淋巴瘤的 61 岁女性接受了氟-18-脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（[¹⁸F]FDG PET/CT）进行分期。由于脊髓和大脑明显摄取[¹⁸F]FDG，因此在正电子发射断层扫描/计算机断层扫描（PET/CT）之后进行了正电子发射断层扫描/磁共振成像（PET/MRI）。图像显示脊髓弥漫性摄取[¹⁸F]FDG，MRI显示T2信号强度增高，怀疑为淋巴瘤受累。患者被诊断为弥漫大B细胞淋巴瘤，累及右颌面部、右颈淋巴结、宫颈、大脑和脊髓（非生殖中心B细胞源IV期）。化疗后，脊髓[¹⁸F]FDG摄取水平明显下降，被认为是部分代谢反应。我们的病例与之前的病例不同，它表明淋巴瘤累及脊髓的模式是局灶性的。
Diffuse lymphoma involvement of the spinal cord showed on [18F]FDG PET/MRI.
A 61-year-old woman with diffuse large B-cell lymphoma received a fluorine-18-deoxyglucose positron emission tomography/computed tomography ([¹⁸F]FDG PET/CT) for staging. Because of the obvious uptake of [¹⁸F]FDG in the spinal cord and brain, a positron emission tomography/magnetic resonance imaging (PET/MRI) was performed after the positron emission tomography/computed tomography (PET/CT). The images showed diffuse [¹⁸F]FDG uptake of the spinal cord and increased T2 signal intensity on MRI, which was suspected to be lymphoma involvement. The patient was diagnosed with diffuse large B-cell lymphoma involving the right maxillofacial region, right cervical lymph nodes, cervix, brain and spinal cord (stage IV of non-germinal center B-cell origin). After chemotherapy, the spinal [¹⁸F]FDG uptake level decreased significantly, which was considered to be a partial metabolic response. Our case was different from prior, which indicated the pattern of spinal cord involvement by lymphoma was focal.
期刊介绍：
Written in English, NMR is a biannual international periodical of scientific and educational profile. It is a journal of Bulgarian, Czech, Hungarian, Macedonian, Polish, Romanian, Russian, Slovak, Ukrainian and Yugoslav Societies of Nuclear Medicine. The periodical focuses on all nuclear medicine topics (diagnostics as well as therapy), and presents original experimental scientific papers, reviews, case studies, letters also news about symposia and congresses. NMR is indexed at Index Copernicus (7.41), Scopus, EMBASE, Index Medicus/Medline, Ministry of Education 2007 (4 pts.).
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