[脑膜瘤切除术前栓塞可能抑制肿瘤复发]

Q4 Medicine
Taisuke Akimoto, Yasunobu Nakai
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引用次数: 0

摘要

血管内治疗的最新进展提高了这一手术的安全性和有效性,术前栓塞的病例数可能会增加。术前肿瘤栓塞仍是一种有争议的治疗方法,只要它存在并发症风险,其减少手术失血的主要益处可能就不足以证明治疗的合理性。我们最近报告说,术前栓塞不会明显增加并发症,但可以延长无复发生存期。不过,目前肿瘤栓塞只是一种术前辅助疗法,没有证据表明它是脑膜瘤治疗的独立选择。不过,也有报道称,单独使用肿瘤栓塞可促进肿瘤缩小并减轻周围水肿,但病例数较少。肿瘤栓塞术还需要进一步的研究,但在未来,肿瘤栓塞术可能会在某些情况下成为一种诊室内治疗方法,如全身状况不佳、多发性脑膜瘤、复发和难治性病例、手术困难以及放疗后再放疗困难的病例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Preoperative Embolization Performed Before Meningioma Resection Might Inhibit Tumor Recurrence].

Recent advances in endovascular treatment have improved the safety and efficacy of this procedure, and the number of cases in which preoperative embolization is performed is likely to increase. Preoperative tumor embolization is still a controversial treatment, and as long as it carries a risk of complications, its primary benefit of reducing blood loss during surgery may not be sufficient to justify treatment. We recently reported that preoperative embolization does not significantly increase complications, but may prolong recurrence-free survival. However, currently, tumor embolization is only a preoperative adjunctive therapy, and there is no evidence that it is a stand-alone option for meningioma treatment. Nevertheless, the possibility that tumor embolization alone can promote tumor shrinkage and reduce peripheral oedema has been reported, although the number of cases is small. Further research is needed, but in the future, tumor embolization may become an in-office treatment under certain conditions, such as in cases of poor general condition, multiple meningiomas, recurrent and refractory cases, difficult surgery and cases where re-irradiation is difficult after post-radiation therapy.

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来源期刊
Neurological Surgery
Neurological Surgery Medicine-Medicine (all)
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