一期后路联合手术和椎板成形术-Alone治疗伴有前后压迫的多级退行性颈椎病的长期疗效:8年随访倾向得分匹配分析》。

IF 2.6 3区 医学 Q2 CLINICAL NEUROLOGY
Ruomu Qu, Yiyuan Yang, Ben Wang, Zexiang Liu, Xiumao Li, Liang Jiang, Xiaoguang Liu, Zhongjun Liu
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引用次数: 0

摘要

研究设计回顾性队列研究:本研究旨在探讨单纯椎板成形术(LP)和联合术(CP)(包括椎板成形术和单水平颈椎前路椎间盘切除术和融合术)在多水平退行性颈椎脊髓病(MDCM)合并前后压迫(CAPC)患者中的长期疗效:方法: 2012年至2015年期间,同一手术组连续对接受LP或CP治疗的多椎间孔变性颈椎病(MDCM)合并前后压迫症(CAPC)患者进行了登记和至少8年的随访。收集术前人口统计学、放射学和临床变量。进行倾向评分匹配(PSM)分析,以匹配病情相似的患者。通过术后日本骨科协会(JOA)评分改善情况、JOA恢复率(JOARR)和并发症对结果进行评估:结果:共纳入 230 名患者,其中 146 人接受了 LP,84 人接受了 CP。经过 PSM,84 对具有可比性的患者进行了配对。配对组在术前条件方面具有相当的可比性。CP 组的手术时间明显延长,失血量增加。最终随访时,LP 组和 CP 组的术后 JOA 评分分别为(14.51 ± 1.79)和(15.47 ± 1.81)(P < 0.001),JOARR 分别为(42.5% ± 53.3%)和(68.5% ± 35.4%)(P < 0.001)。LP组有3名(3.6%)患者因症状复发而再次手术(P = 0.081):结论:LP和CP均可使CAPC患者的神经功能得到显著的长期恢复。结论:LP 和 CP 对 CAPC 患者的长期神经恢复都很明显,CP 的 JOA 改善和 JOARR 明显更高。在治疗伴有 CAPC 的 MDCM 时,经验丰富的医生可能会将联合减压作为一种安全有效的替代方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-Term Outcomes of One-Stage Combined Posteroanterior Procedure and Laminoplasty-Alone for Multilevel Degenerative Cervical Myelopathy With Concomitant Anterior and Posterior Compression: A Propensity Score Matching Analysis of 8-year Follow-Up.

Study design: Retrospective cohort study.

Objective: This study aimed to investigate the long-term outcomes of laminoplasty-alone (LP) and combined procedure (CP), consisting of laminoplasty and single-level anterior cervical discectomy and fusion, in comparable patients who had multilevel degenerative cervical myelopathy (MDCM) with concomitant anterior and posterior compression (CAPC).

Methods: Consecutive MDCM patients with CAPC underwent LP or CP between 2012 and 2015 from a same surgical group were enrolled and followed up for a minimum of 8 years. Preoperative demographic, radiological, and clinical variables were collected. Propensity score matching (PSM) analysis was performed to match patients with comparable conditions. The outcomes were evaluated by postoperative Japanese Orthopedic Association (JOA) score improvement, JOA recovery rate (JOARR) and complications.

Results: A total of 230 patients were included, of whom 146 underwent LP and 84 underwent CP. After PSM, 84 pairs of comparable patients were matched. The matched groups presented fair comparability in preoperative conditions. The CP group had significantly prolonged surgery time and greater blood loss. At the final follow-up, the postoperative JOA scores of LP and CP groups were 14.51 ± 1.79 and 15.47 ± 1.81 (P < 0.001) and the JOARR were 42.5% ± 53.3% and 68.5% ± 35.4%, respectively (P < 0.001). Three (3.6%) patients in the LP group underwent reoperations because of recurrent symptoms (P = 0.081).

Conclusion: Both LP and CP demonstrated considerable long-term neurological recovery in patients with CAPC. The CP showed a significantly higher JOA improvement and JOARR. The combined decompression might be a safe and effective alternative in treating MDCM with CAPC in experienced hands.

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来源期刊
Global Spine Journal
Global Spine Journal Medicine-Surgery
CiteScore
6.20
自引率
8.30%
发文量
278
审稿时长
8 weeks
期刊介绍: Global Spine Journal (GSJ) is the official scientific publication of AOSpine. A peer-reviewed, open access journal, devoted to the study and treatment of spinal disorders, including diagnosis, operative and non-operative treatment options, surgical techniques, and emerging research and clinical developments.GSJ is indexed in PubMedCentral, SCOPUS, and Emerging Sources Citation Index (ESCI).
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