{"title":"血浆蛋白对糖尿病酮症酸中毒患者的复苏有益吗？综述。","authors":"Resshme Kannan Sudha, Kinza Moin, Falaah Abdul Hameed, Hamid Aizaz Chatha","doi":"10.15441/ceem.24.209","DOIUrl":null,"url":null,"abstract":"<p><p>Fluid resuscitation is vital in the treatment of diabetic ketoacidosis (DKA) patients. The purpose of this narrative review is to analyze the role of Plasmalyte in the fluid resuscitation of adult DKA patients. A thorough search was conducted in PubMed, MEDLINE, and Embase. Studies conducted between January 1, 2010, and March 31, 2023, were collected. Of 123 results, five pertinent randomized controlled trials were included. The close resemblance of Plasmalyte's electrolyte composition to that of human plasma, and its role in the prevention of hyperchloremic metabolic acidosis are some of its key benefits in patients with diabetic ketoacidosis. Plasmalyte's role in length of stay, time to resolution of diabetic ketoacidosis, and mortality in DKA patients varied among studies. Hence, further research on these topics is needed.</p>","PeriodicalId":10325,"journal":{"name":"Clinical and Experimental Emergency Medicine","volume":" ","pages":"104-109"},"PeriodicalIF":1.9000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245647/pdf/","citationCount":"0","resultStr":"{\"title\":\"Is Plasmalyte beneficial in the resuscitation of diabetic ketoacidosis patients? A narrative review.\",\"authors\":\"Resshme Kannan Sudha, Kinza Moin, Falaah Abdul Hameed, Hamid Aizaz Chatha\",\"doi\":\"10.15441/ceem.24.209\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Fluid resuscitation is vital in the treatment of diabetic ketoacidosis (DKA) patients. The purpose of this narrative review is to analyze the role of Plasmalyte in the fluid resuscitation of adult DKA patients. A thorough search was conducted in PubMed, MEDLINE, and Embase. Studies conducted between January 1, 2010, and March 31, 2023, were collected. Of 123 results, five pertinent randomized controlled trials were included. The close resemblance of Plasmalyte's electrolyte composition to that of human plasma, and its role in the prevention of hyperchloremic metabolic acidosis are some of its key benefits in patients with diabetic ketoacidosis. Plasmalyte's role in length of stay, time to resolution of diabetic ketoacidosis, and mortality in DKA patients varied among studies. Hence, further research on these topics is needed.</p>\",\"PeriodicalId\":10325,\"journal\":{\"name\":\"Clinical and Experimental Emergency Medicine\",\"volume\":\" \",\"pages\":\"104-109\"},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12245647/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical and Experimental Emergency Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15441/ceem.24.209\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/7/19 0:00:00\",\"PubModel\":\"Epub\",\"JCR\":\"Q2\",\"JCRName\":\"EMERGENCY MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical and Experimental Emergency Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15441/ceem.24.209","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/7/19 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"EMERGENCY MEDICINE","Score":null,"Total":0}
Is Plasmalyte beneficial in the resuscitation of diabetic ketoacidosis patients? A narrative review.
Fluid resuscitation is vital in the treatment of diabetic ketoacidosis (DKA) patients. The purpose of this narrative review is to analyze the role of Plasmalyte in the fluid resuscitation of adult DKA patients. A thorough search was conducted in PubMed, MEDLINE, and Embase. Studies conducted between January 1, 2010, and March 31, 2023, were collected. Of 123 results, five pertinent randomized controlled trials were included. The close resemblance of Plasmalyte's electrolyte composition to that of human plasma, and its role in the prevention of hyperchloremic metabolic acidosis are some of its key benefits in patients with diabetic ketoacidosis. Plasmalyte's role in length of stay, time to resolution of diabetic ketoacidosis, and mortality in DKA patients varied among studies. Hence, further research on these topics is needed.
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