A. Michán-Doña , E. Jiménez-Varo , M. Escribano-Cobalea , C. Casto-Jarillo , A. López-Ceres , E. Campos-Dávila , A. Hormigo-Pozo , C. Nieto-Ordoñez , M.Á. Rodríguez-Juliá , J. Escribano-Serrano
{"title":"加的斯(西班牙)一个健康地区 50 岁及以上糖尿病患者贫血症的患病率和特征。","authors":"A. Michán-Doña , E. Jiménez-Varo , M. Escribano-Cobalea , C. Casto-Jarillo , A. López-Ceres , E. Campos-Dávila , A. Hormigo-Pozo , C. Nieto-Ordoñez , M.Á. Rodríguez-Juliá , J. Escribano-Serrano","doi":"10.1016/j.rce.2024.05.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p>Anemia is a common comorbidity in patients with diabetes mellitus (DM), particularly in older adults. However, there is a lack of data on the prevalence and the characteristics of anemia in this population in Spain.</p></div><div><h3>Objective</h3><p>To describe the prevalence and the characteristics of anemia in patients with DM aged 50 or older (PDM50) in a healthcare district in the province of Cádiz.</p></div><div><h3>Methods</h3><p>A retrospective cross-sectional study was conducted that included outpatient's laboratory tests (OLT) performed over 30 months at PDM50.</p></div><div><h3>Results</h3><p>The prevalence of anemia was 29.9% (95% CI: 28.7-31.1%), predominating in women (33.3% vs 26.7%; p<<!--> <!-->0.01), in older people stratified by decades (61.7% in 9<!--> <!-->th decade vs 12% in 5<!--> <!-->th decade; p<<!--> <!-->0.01), and in those with kidney disease (44.7% vs 28%; p<<!--> <!-->0.01). Most cases were mild (68.3%), normocytic (78.7%), and hypochromic (52%). Similarly, moderate-to-severe anemia was more frequent in women (39% vs 23%), their prevalence increased with age (45% in the 9<!--> <!-->th decade vs 24% in the 5<!--> <!-->th decade), and with the progression of kidney damage, either measured by a decreased glomerular filtration rate (GFR) (49% in G4 vs 25% in G1), or the presence of albuminuria (p<!--> <!--><<!--> <!-->0.01). No association was found between DM control, based on glycated hemoglobin (HbA1c), and anemia in either sex (p<!--> <!-->=<!--> <!-->0.887).</p></div><div><h3>Conclusion</h3><p>This study describes a high prevalence of anemia in PDM50, particularly in women, in the most advantageous people and in the presence of kidney disease, even in early stages, highlighting the clinical importance of this coexistence.</p></div>","PeriodicalId":21223,"journal":{"name":"Revista clinica espanola","volume":"224 7","pages":"Pages 457-465"},"PeriodicalIF":2.3000,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalencia y características de la anemia en personas con diabetes mellitus de 50 años o más en un área sanitaria de Cádiz (España)\",\"authors\":\"A. Michán-Doña , E. Jiménez-Varo , M. Escribano-Cobalea , C. Casto-Jarillo , A. López-Ceres , E. Campos-Dávila , A. Hormigo-Pozo , C. Nieto-Ordoñez , M.Á. Rodríguez-Juliá , J. Escribano-Serrano\",\"doi\":\"10.1016/j.rce.2024.05.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><p>Anemia is a common comorbidity in patients with diabetes mellitus (DM), particularly in older adults. However, there is a lack of data on the prevalence and the characteristics of anemia in this population in Spain.</p></div><div><h3>Objective</h3><p>To describe the prevalence and the characteristics of anemia in patients with DM aged 50 or older (PDM50) in a healthcare district in the province of Cádiz.</p></div><div><h3>Methods</h3><p>A retrospective cross-sectional study was conducted that included outpatient's laboratory tests (OLT) performed over 30 months at PDM50.</p></div><div><h3>Results</h3><p>The prevalence of anemia was 29.9% (95% CI: 28.7-31.1%), predominating in women (33.3% vs 26.7%; p<<!--> <!-->0.01), in older people stratified by decades (61.7% in 9<!--> <!-->th decade vs 12% in 5<!--> <!-->th decade; p<<!--> <!-->0.01), and in those with kidney disease (44.7% vs 28%; p<<!--> <!-->0.01). Most cases were mild (68.3%), normocytic (78.7%), and hypochromic (52%). Similarly, moderate-to-severe anemia was more frequent in women (39% vs 23%), their prevalence increased with age (45% in the 9<!--> <!-->th decade vs 24% in the 5<!--> <!-->th decade), and with the progression of kidney damage, either measured by a decreased glomerular filtration rate (GFR) (49% in G4 vs 25% in G1), or the presence of albuminuria (p<!--> <!--><<!--> <!-->0.01). No association was found between DM control, based on glycated hemoglobin (HbA1c), and anemia in either sex (p<!--> <!-->=<!--> <!-->0.887).</p></div><div><h3>Conclusion</h3><p>This study describes a high prevalence of anemia in PDM50, particularly in women, in the most advantageous people and in the presence of kidney disease, even in early stages, highlighting the clinical importance of this coexistence.</p></div>\",\"PeriodicalId\":21223,\"journal\":{\"name\":\"Revista clinica espanola\",\"volume\":\"224 7\",\"pages\":\"Pages 457-465\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista clinica espanola\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0014256524001127\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista clinica espanola","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0014256524001127","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Prevalencia y características de la anemia en personas con diabetes mellitus de 50 años o más en un área sanitaria de Cádiz (España)
Background
Anemia is a common comorbidity in patients with diabetes mellitus (DM), particularly in older adults. However, there is a lack of data on the prevalence and the characteristics of anemia in this population in Spain.
Objective
To describe the prevalence and the characteristics of anemia in patients with DM aged 50 or older (PDM50) in a healthcare district in the province of Cádiz.
Methods
A retrospective cross-sectional study was conducted that included outpatient's laboratory tests (OLT) performed over 30 months at PDM50.
Results
The prevalence of anemia was 29.9% (95% CI: 28.7-31.1%), predominating in women (33.3% vs 26.7%; p< 0.01), in older people stratified by decades (61.7% in 9 th decade vs 12% in 5 th decade; p< 0.01), and in those with kidney disease (44.7% vs 28%; p< 0.01). Most cases were mild (68.3%), normocytic (78.7%), and hypochromic (52%). Similarly, moderate-to-severe anemia was more frequent in women (39% vs 23%), their prevalence increased with age (45% in the 9 th decade vs 24% in the 5 th decade), and with the progression of kidney damage, either measured by a decreased glomerular filtration rate (GFR) (49% in G4 vs 25% in G1), or the presence of albuminuria (p < 0.01). No association was found between DM control, based on glycated hemoglobin (HbA1c), and anemia in either sex (p = 0.887).
Conclusion
This study describes a high prevalence of anemia in PDM50, particularly in women, in the most advantageous people and in the presence of kidney disease, even in early stages, highlighting the clinical importance of this coexistence.
期刊介绍:
Revista Clínica Española published its first issue in 1940 and is the body of expression of the Spanish Society of Internal Medicine (SEMI).
The journal fully endorses the goals of updating knowledge and facilitating the acquisition of key developments in internal medicine applied to clinical practice. Revista Clínica Española is subject to a thorough double blind review of the received articles written in Spanish or English. Nine issues are published each year, including mostly originals, reviews and consensus documents.