L. A. Mohammed, Ahmed Medhat Hegazy, W. E. El gazzar, N. El-shaer, Heba Bayoumi, Salwa A. Elgendy, Heba A. Elnoury, H. E. Nasr
{"title":"白藜芦醇通过引发自噬和抑制 mTOR 通路对大鼠 2 型糖尿病有改善作用。","authors":"L. A. Mohammed, Ahmed Medhat Hegazy, W. E. El gazzar, N. El-shaer, Heba Bayoumi, Salwa A. Elgendy, Heba A. Elnoury, H. E. Nasr","doi":"10.21608/besps.2024.279336.1166","DOIUrl":null,"url":null,"abstract":"Background: Type 2 diabetes mellitus (T2DM), which affects millions of individuals, has become a serious health problem.The mammalian target of rapamycin (mTOR) hyperactivation is a negatively involved autophagy that may in fact aid in the loss of β -cell function.Resveratrol (RSV) is a naturally occurring phytoalexin, mostly found incereals, fruits","PeriodicalId":9347,"journal":{"name":"Bulletin of Egyptian Society for Physiological Sciences","volume":"67 6","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ameliorative effect of resveratrol against type 2 diabetes in rats through triggering of autophagy and inhibition of mTOR pathway.\",\"authors\":\"L. A. Mohammed, Ahmed Medhat Hegazy, W. E. El gazzar, N. El-shaer, Heba Bayoumi, Salwa A. Elgendy, Heba A. Elnoury, H. E. Nasr\",\"doi\":\"10.21608/besps.2024.279336.1166\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background: Type 2 diabetes mellitus (T2DM), which affects millions of individuals, has become a serious health problem.The mammalian target of rapamycin (mTOR) hyperactivation is a negatively involved autophagy that may in fact aid in the loss of β -cell function.Resveratrol (RSV) is a naturally occurring phytoalexin, mostly found incereals, fruits\",\"PeriodicalId\":9347,\"journal\":{\"name\":\"Bulletin of Egyptian Society for Physiological Sciences\",\"volume\":\"67 6\",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bulletin of Egyptian Society for Physiological Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/besps.2024.279336.1166\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of Egyptian Society for Physiological Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/besps.2024.279336.1166","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Ameliorative effect of resveratrol against type 2 diabetes in rats through triggering of autophagy and inhibition of mTOR pathway.
Background: Type 2 diabetes mellitus (T2DM), which affects millions of individuals, has become a serious health problem.The mammalian target of rapamycin (mTOR) hyperactivation is a negatively involved autophagy that may in fact aid in the loss of β -cell function.Resveratrol (RSV) is a naturally occurring phytoalexin, mostly found incereals, fruits