采用主动脉瓣再植入技术治疗 DeBakey 1 型主动脉夹层的早期和短期疗效

Mohamed A. Shaban, Abdallah Nosair, Eman Salah, Eldin Elsakaan, Ahmed Sultan, Mohamed Shehata, Hisham M. Elbatanony
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引用次数: 0

摘要

背景:急性主动脉夹层是一种危重病症,有很大的死亡和发病风险。Bentall 手术已成为治疗主动脉根部病变的公认标准。新的趋势是进行主动脉瓣保留手术,以防止与人工瓣膜相关的各种风险。研究目的本研究的主要目的是评估采用主动脉瓣再植入技术(Tirone David)治疗 DeBakey 1 型主动脉夹层的早期和短期效果,包括心功能评估、主要心脏问题、临床状态、生活质量和随访 1 年的死亡率。患者和方法:这项回顾性研究纳入了 49 名急性主动脉夹层 DeBakey 1 型患者,他们均伴有严重的主动脉瓣关闭不全(AI)、涉及升主动脉的壁内血肿和/或升主动脉穿透性动脉粥样硬化溃疡。他们采用主动脉瓣再植技术(Tirone David)进行了手术。手术结果平均年龄为(54.15±13.77)岁。术中死亡率为 0%,手术死亡率为 5(10.20%),无晚期死亡率,1 年总存活率为 44(89.80%)。总体住院并发症发生率为13(26.53%)。随访1年后,左心室射血分数百分比(LVEF%)、左心室舒张末期直径(LVEDD)(P<0.001)、左心室收缩末期直径(LVESD)(P<0.001)和AI程度均有显著改善。LVEF 从术前的 52.54±9.16% 提高到 55.67±8.35%(P=0.015)。AI程度从100%的重度AI改善到28例(63.63%)无AI或轻度AI,15例(34.09%)轻度AI,1例(2.27%)中度AI,无重度AI患者(P<0.001)。没有出现主动脉瓣(AV)功能衰竭的并发症。结论在适当的情况下,建议通过再植技术(Tirone David 手术)保留患者的原生主动脉瓣,因为这样可以改善左心室功能,避免发生瓣膜相关并发症(心内膜炎、血栓栓塞并发症和终身抗凝)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Early and Short-term Outcomes of Adopting Aortic Valve Re-Implantation Technique Addressing DeBakey Type 1 Aortic Dissection
Background: Acute aortic dissection is a critical medical condition that has a significant risk of death and morbidity. The Bentall procedure has become the accepted standard for treating aortic root pathology. The newer trend is to perform the aortic valve-sparing operations to prevent various risks related to prosthetic valves. Objective: This study primarily aimed at assessment of the early and short-term results of adopting aortic valve re-implantation technique (Tirone David) addressing DeBakey Type 1 aortic dissection including cardiac function assessment, major cardiac problems, clinical status, quality of life and mortality over 1-year follow-up. Patients and Methods: This retrospective study included 49 patients with acute aortic dissection DeBakeytype 1 associated with severe aortic incompetence (AI), intramural hematoma involving the ascending aorta and/or penetrating atherosclerotic ulcer in the ascending aorta. They were operated upon using aortic valve re-implantation technique (Tirone David). Results: The mean age was 54.15±13.77 years. Mortality was 0% intraoperatively, 5(10.20%) operative mortality, no late mortality and the overall 1-year survival rate was 44(89.80%). The overall hospital complications rate was13 (26.53%). At 1-year follow-up, there were statistically significant improvements in left ventricular ejection fraction per cent (LVEF%), left ventricular end-diastolic diameter (LVEDD)(p<0.001), left ventricular end-systolic diameter (LVESD) (p<0.001) and AI degree. LVEF improved from 52.54±9.16% preoperatively to 55.67±8.35% (p=0.015). AI degree improved from severe AI in 100% of cases to no or trivial AI in 28(63.63%) patients, mild AI in 15(34.09%) patients, moderate AI in 1(2.27%) patient and no patients with severe AI (p<0.001). There were no complications in the form of aortic valve (AV) failure. Conclusion: The procedure of preservation of the patient’s native aortic valve through re-implantation technique (Tirone David operation), when appropriate, is recommended as it allows better left ventricular performance and avoiding the development of valve-related complications (endocarditis, thromboembolic complications and life-long anticoagulation).
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